Anti-FRAT1 Antibody (CAB16093)
- SKU:
- CAB16093
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-FRAT1 Antibody |
抗体コード: | CAB16093 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human FRAT1 (NP_005470.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse thymus, Mouse spleen, Rat testis, Rat spleen |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human FRAT1 (NP_005470.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | HRLL QQLV LSGN LIKE AVRR LHSR RLQL RAKL PQRP LLGP LSAP VHEP PSPR SPRA ACSD PGAS GRAQ LRTG DGVL VPGS |
遺伝子ID: | 10023 |
Uniprot: | Q92837 |
セルラーロケーション: | Cytoplasm |
計算された分子量: | 29kDa |
観察された分子量: | 31kDa |
同義語: | FRAT1 |
バックグラウンド: | The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. |
UniProt Protein Function: | FRAT1: Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. Belongs to the GSK-3-binding protein family. |
UniProt Protein Details: | Protein type:Oncoprotein; Transcription regulation Chromosomal Location of Human Ortholog: 10q24.1 Cellular Component: cytosol |
NCBI Summary: | The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq, Oct 2008] |
UniProt Code: | Q92837 |
NCBI GenInfo Identifier: | 51338813 |
NCBI Gene ID: | 10023 |
NCBI Accession: | Q92837.3 |
UniProt Secondary Accession: | Q92837,Q5JTI1, Q8NE74, Q8TDW9, |
UniProt Related Accession: | Q92837 |
Molecular Weight: | 29,093 Da |
NCBI Full Name: | Proto-oncogene FRAT1 |
NCBI Synonym Full Names: | frequently rearranged in advanced T-cell lymphomas 1 |
NCBI Official Symbol: | FRAT1 |
NCBI Protein Information: | proto-oncogene FRAT1 |
UniProt Protein Name: | Proto-oncogene FRAT1 |
UniProt Synonym Protein Names: | Frequently rearranged in advanced T-cell lymphomas 1; FRAT-1 |
Protein Family: | F1 capsule antigen |
UniProt Gene Name: | FRAT1 |
UniProt Entry Name: | FRAT1_HUMAN |
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