Anti-FOXE1 Antibody (CAB12628)
- SKU:
- CAB12628
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-FOXE1 Antibody |
抗体コード: | CAB12628 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 184-373 of human FOXE1 (NP_004464.2). |
申し込み: | WB |
推奨希釈: | WB 1:1000 - 1:2000 |
反応性: | Human |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 184-373 of human FOXE1 (NP_004464.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | AVPA ARPP YPGA VYAG YAPP SLAA PPPV YYPA ASPG PCRV FGLV PERP LSPE LGPA PSGP GGSC AFAS AGAP ATTT GYQP AGCT GARP ANPS AYAA AYAG PDGA YPQG AGSA IFAA AGRL AGPA SPPA GGSS GGVE TTVD FYGR TSPG QFGA LGAC YNPG GQLG GASA GAYH ARHA AAYP GGID RFVS AM |
遺伝子ID: | 2304 |
Uniprot: | O00358 |
セルラーロケーション: | Nucleus |
計算された分子量: | 38kDa |
観察された分子量: | Refer to Figures |
同義語: | FOXE1, FKHL15, FOXE2, HFKH4, HFKL5, NMTC4, TITF2, TTF-2, TTF2 |
バックグラウンド: | This intronless gene encodes a protein that belongs to the forkhead family of transcription factors. Members of this family contain a conserved 100-amino acid DNA-binding 'forkhead' domain. The encoded protein functions as a thyroid transcription factor that plays a role in thyroid morphogenesis. Mutations in this gene are associated with the Bamforth-Lazarus syndrome, and with susceptibility to nonmedullary thyroid cancer-4. |
UniProt Protein Function: | Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression. |
NCBI Summary: | This intronless gene encodes a protein that belongs to the forkhead family of transcription factors. Members of this family contain a conserved 100-amino acid DNA-binding 'forkhead' domain. The encoded protein functions as a thyroid transcription factor that plays a role in thyroid morphogenesis. Mutations in this gene are associated with the Bamforth-Lazarus syndrome, and with susceptibility to nonmedullary thyroid cancer-4. [provided by RefSeq, Nov 2016] |
UniProt Code: | O00358 |
NCBI GenInfo Identifier: | 21618325 |
NCBI Gene ID: | 2304 |
NCBI Accession: | NP_004464.2 |
UniProt Secondary Accession: | O00358,O75765, Q5T109, Q99526, |
UniProt Related Accession: | O00358 |
Molecular Weight: | Observed: 34 kDaPredicted: 39 kDa |
NCBI Full Name: | forkhead box protein E1 |
NCBI Synonym Full Names: | forkhead box E1 |
NCBI Official Symbol: | FOXE1 |
NCBI Official Synonym Symbols: | TTF2; FOXE2; HFKH4; HFKL5; NMTC4; TITF2; TTF-2; FKHL15 |
NCBI Protein Information: | forkhead box protein E1 |
UniProt Protein Name: | Forkhead box protein E1 |
UniProt Synonym Protein Names: | Forkhead box protein E2; Forkhead-related protein FKHL15; HFKH4; HNF-3/fork head-like protein 5; HFKL5; Thyroid transcription factor 2; TTF-2 |
Protein Family: | Transcription termination factor |
UniProt Gene Name: | FOXE1 |
View AllClose