Anti-FECH Antibody (CAB8418)
- SKU:
- CAB8418
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-FECH Antibody |
抗体コード: | CAB8418 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FECH (NP_000131.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HepG2, HT-29, Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FECH (NP_000131.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MRSL GANM AAAL RAAG VLLR DPLA SSSW RVCQ PWRW KSGA AAAA VTTE TAQH AQGA KPQV QPQK RKPK TGIL MLNM GGPE TLGD VHDF LLRL FLDR DLMT LPIQ NKLA PFIA KRRT PKIQ EQYR RIGG GSPI KIWT SKQG EGMV KLLD ELSP NTAP HKYY IGFR YVHP LTEE AIEE MERD GLER AIAF TQYP QYSC STTG |
遺伝子ID: | 2235 |
Uniprot: | P22830 |
セルラーロケーション: | Matrix side, Mitochondrion inner membrane, Peripheral membrane protein |
計算された分子量: | 47kDa/48kDa |
観察された分子量: | 50kDa |
同義語: | FECH, EPP, FCE |
バックグラウンド: | The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3. |
UniProt Code: | P22830 |
NCBI GenInfo Identifier: | 60499021 |
NCBI Gene ID: | 2235 |
NCBI Accession: | NP_000131 |
UniProt Secondary Accession: | P22830,Q8IXN1, Q8NAN0, A8KA72, |
UniProt Related Accession: | P22830 |
Molecular Weight: | 48,625 Da |
NCBI Full Name: | ferrochelatase, mitochondrial isoform b |
NCBI Synonym Full Names: | ferrochelatase |
NCBI Official Symbol: | FECH |
NCBI Official Synonym Symbols: | EPP; FCE |
NCBI Protein Information: | ferrochelatase, mitochondrial; heme synthase; heme synthetase; protoheme ferro-lyase; protoporphyria |
UniProt Protein Name: | Ferrochelatase, mitochondrial |
UniProt Synonym Protein Names: | Heme synthase; Protoheme ferro-lyase |
UniProt Gene Name: | FECH |
UniProt Entry Name: | HEMH_HUMAN |
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