Anti-FCN2 Antibody (CAB16690)
- SKU:
- CAB16690
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
抗体名: | Anti-FCN2 Antibody |
抗体コード: | CAB16690 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 230-290 of human FCN2 (NP_004099.2). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | mosue spleen, mouse lung, rat spleen |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 230-290 of human FCN2 (NP_004099.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SAGD SLTF HNNQ SFST KDQD NDLN TGNC AVMF QGAW WYKN CHVS NLNG RYLR GTHG SFAN G |
遺伝子ID: | 2220 |
Uniprot: | Q15485 |
セルラーロケーション: | |
計算された分子量: | 34kDa |
観察された分子量: | 34kDa |
同義語: | FCN2, EBP-37, FCNL, P35, ficolin-2 |
バックグラウンド: | The product of this gene belongs to the ficolin family of proteins. This family is characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. This gene is predominantly expressed in the liver, and has been shown to have carbohydrate binding and opsonic activities. Alternatively spliced transcript variants encoding different isoforms have been identified. |
UniProt Protein Function: | FCN2: May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region. Belongs to the ficolin lectin family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 9q34 |
NCBI Summary: | The product of this gene belongs to the ficolin family of proteins. This family is characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. This gene is predominantly expressed in the liver, and has been shown to have carbohydrate binding and opsonic activities. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q15485 |
NCBI GenInfo Identifier: | 166214934 |
NCBI Gene ID: | 2220 |
NCBI Accession: | Q15485.2 |
UniProt Secondary Accession: | Q15485,Q6IS69, Q7M4P4, Q9UC57, A6NFG7, A8K478, |
UniProt Related Accession: | Q15485 |
Molecular Weight: | 30,228 Da |
NCBI Full Name: | Ficolin-2 |
NCBI Synonym Full Names: | ficolin (collagen/fibrinogen domain containing lectin) 2 |
NCBI Official Symbol: | FCN2 |
NCBI Official Synonym Symbols: | P35; FCNL; EBP-37; ficolin-2 |
NCBI Protein Information: | ficolin-2; L-ficolin; ficolin B; ficolin-B; ficolin-beta; serum lectin p35; 37 kDa elastin-binding protein; collagen/fibrinogen domain-containing protein 2; ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) |
UniProt Protein Name: | Ficolin-2 |
UniProt Synonym Protein Names: | 37 kDa elastin-binding protein; Collagen/fibrinogen domain-containing protein 2; EBP-37; Ficolin-B; Ficolin-beta; Hucolin; L-ficolin; Serum lectin p35 |
Protein Family: | Ficolin |
UniProt Gene Name: | FCN2 |
UniProt Entry Name: | FCN2_HUMAN |
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