Anti-FARS2 Antibody (CAB15246)
- SKU:
- CAB15246
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-FARS2 Antibody |
抗体コード: | CAB15246 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human FARS2 (NP_006558.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Rat |
ポジティブサンプル: | A549, rat kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human FARS2 (NP_006558.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MVGS ALRR GAHA YVYL VSKA SHIS RGHQ HQAW GSRP PAAE CATQ RAPG SVVE LLGK SYPQ DDHS NLTR KVLT RVGR NLHN QQHH PLWL IKER VKEH FYKQ YVGR FGTP LFSV YDNL SPVV TTWQ NFDS LLIP ADHP SRKK GDNY YLNR THML RAHT SAHQ WDLL HAGL DAFL VVGD VYRR DQID SQHY PIFH QLEA VRLF SKHE LFAG IKDG ESLQ LFEQ SSRS AHKQ ETHT MEAV KLVE FDLK QTLT RL |
遺伝子ID: | 10667 |
Uniprot: | O95363 |
セルラーロケーション: | Mitochondrion matrix |
計算された分子量: | 52kDa |
観察された分子量: | 52kDa |
同義語: | FARS2, COXPD14, FARS1, HSPC320, PheRS, SPG77 |
バックグラウンド: | This gene encodes a protein that transfers phenylalanine to its cognate tRNA. This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation. Mutations in this gene can cause combined oxidative phosphorylation deficiency 14 (Alpers encephalopathy). Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | FARS2: Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins. Belongs to the class-II aminoacyl-tRNA synthetase family. |
UniProt Protein Details: | Protein type:EC 6.1.1.20; RNA-binding; Translation; Mitochondrial; Ligase Chromosomal Location of Human Ortholog: 6p25.1 Cellular Component: mitochondrial matrix Molecular Function:phenylalanine-tRNA ligase activity; magnesium ion binding; ATP binding; tRNA binding Biological Process: tRNA aminoacylation for protein translation; tRNA processing; phenylalanyl-tRNA aminoacylation; gene expression Disease: Combined Oxidative Phosphorylation Deficiency 14 |
UniProt Code: | O95363 |
NCBI GenInfo Identifier: | 15341941 |
NCBI Gene ID: | 64108 |
NCBI Accession: | BC013161 |
UniProt Secondary Accession: | O95363,Q9H4F3, |
UniProt Related Accession: | Q96DX8 |
Molecular Weight: | 27,863 Da |
NCBI Full Name: | Homo sapiens receptor (chemosensory) transporter protein 4, mRNA |
NCBI Synonym Full Names: | receptor transporter protein 4 |
NCBI Official Symbol: | RTP4 |
NCBI Official Synonym Symbols: | IFRG28; Z3CXXC4 |
NCBI Protein Information: | receptor-transporting protein 4 |
UniProt Protein Name: | Phenylalanine--tRNA ligase, mitochondrial |
UniProt Synonym Protein Names: | Phenylalanyl-tRNA synthetase; PheRS |
Protein Family: | Receptor-transporting protein |
UniProt Gene Name: | FARS2 |
UniProt Entry Name: | SYFM_HUMAN |
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