Anti-FABPI Antibody (CAB8895)
- SKU:
- CAB8895
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-FABPI Antibody |
抗体コード: | CAB8895 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human FABPI |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse small intestine, Rat small intestine |
免疫原: | A synthesized peptide derived from human FABPI |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 2169 |
Uniprot: | P12104 |
セルラーロケーション: | |
計算された分子量: | 15kDa |
観察された分子量: | 14KDa |
同義語: | FABPI, I-FABP |
バックグラウンド: | The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008] |
UniProt Protein Function: | FABP2: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 4q28-q31 Cellular Component: cytoplasm Molecular Function:transporter activity; fatty acid binding Biological Process: transport; digestion |
NCBI Summary: | The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008] |
UniProt Code: | P12104 |
NCBI GenInfo Identifier: | 119805 |
NCBI Gene ID: | 2169 |
NCBI Accession: | P12104.2 |
UniProt Secondary Accession: | P12104,Q2NKJ1, |
UniProt Related Accession: | P12104 |
Molecular Weight: | 132 |
NCBI Full Name: | Fatty acid-binding protein, intestinal |
NCBI Synonym Full Names: | fatty acid binding protein 2, intestinal |
NCBI Official Symbol: | FABP2 |
NCBI Official Synonym Symbols: | FABPI; I-FABP |
NCBI Protein Information: | fatty acid-binding protein, intestinal; fatty acid-binding protein 2; intestinal-type fatty acid-binding protein |
UniProt Protein Name: | Fatty acid-binding protein, intestinal |
UniProt Synonym Protein Names: | Fatty acid-binding protein 2; Intestinal-type fatty acid-binding protein; I-FABP |
Protein Family: | Fatty acid-binding protein |
UniProt Gene Name: | FABP2 |
UniProt Entry Name: | FABPI_HUMAN |
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