Anti-ENPP7 Antibody (CAB2912)
- SKU:
- CAB2912
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-ENPP7 Antibody |
抗体コード: | CAB2912 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A synthetic peptide of human ENPP7 |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | HepG2 |
免疫原: | A synthetic peptide of human ENPP7 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 339221 |
Uniprot: | Q6UWV6 |
セルラーロケーション: | Membrane, Single-pass type I membrane protein |
計算された分子量: | 51kDa |
観察された分子量: | 51kDa |
同義語: | ENPP7, ALK-SMase, E-NPP 7, NPP-7, NPP7, E-NPP7 |
バックグラウンド: | The protein encoded by this gene is an intestinal alkaline sphingomyelin phosphodiesterase that converts sphingomyelin to ceramide and phosphocholine. The encoded protein is anchored in the cell membrane, and it may function to protect the intestinal mucosa from inflammation and tumorigenesis. This protein is glycosylated and also exhibits lysophosphatidylcholine hydrolase activity. |
UniProt Protein Function: | ENPP7: Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. |
UniProt Protein Details: | Protein type:Phosphodiesterase; Lipid Metabolism - sphingolipid; Cell cycle regulation; DNA replication; Motility/polarity/chemotaxis; Membrane protein, integral; EC 3.1.4.12 Chromosomal Location of Human Ortholog: 17q25.3 Cellular Component: Golgi apparatus; microvillus; membrane; integral to membrane; plasma membrane Molecular Function:sphingomyelin phosphodiesterase activity Biological Process: negative regulation of cell proliferation; sphingomyelin metabolic process; sphingolipid metabolic process; negative regulation of DNA replication; glycosphingolipid metabolic process; sphingomyelin catabolic process |
UniProt Code: | Q6UWV6 |
NCBI GenInfo Identifier: | 134047772 |
NCBI Gene ID: | 339221 |
NCBI Accession: | Q6UWV6.3 |
UniProt Secondary Accession: | Q6UWV6,Q6ZTS5, Q8IUS8, |
UniProt Related Accession: | Q6UWV6 |
Molecular Weight: | 458 |
NCBI Full Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 |
NCBI Synonym Full Names: | ectonucleotide pyrophosphatase/phosphodiesterase 7 |
NCBI Official Symbol: | ENPP7 |
NCBI Official Synonym Symbols: | NPP7; NPP-7; E-NPP 7; ALK-SMase |
NCBI Protein Information: | ectonucleotide pyrophosphatase/phosphodiesterase family member 7; ENPP7; alkaline sphingomyelinase; intestinal alkaline sphingomyelinase; alkaline sphingomyelin phosphodiesterase |
UniProt Protein Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 |
UniProt Synonym Protein Names: | Alkaline sphingomyelin phosphodiesterase; Intestinal alkaline sphingomyelinase; Alk-SMase |
Protein Family: | Ectonucleotide pyrophosphatase/phosphodiesterase family |
UniProt Gene Name: | ENPP7 |
UniProt Entry Name: | ENPP7_HUMAN |
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