Anti-EIF5 Antibody (CAB6583)
- SKU:
- CAB6583
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-EIF5 Antibody |
抗体コード: | CAB6583 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-235 of human EIF5 (NP_892116.2). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | MCF7, SW480, HeLa, U-251MG |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-235 of human EIF5 (NP_892116.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MSVN VNRS VSDQ FYRY KMPR LIAK VEGK GNGI KTVI VNMV DVAK ALNR PPTY PTKY FGCE LGAQ TQFD VKND RYIV NGSH EANK LQDM LDGF IKKF VLCP ECEN PETD LHVN PKKQ TIGN SCKA CGYR GMLD THHK LCTF ILKN PPEN SDSG TGKK EKEK KNRK GKDK ENGS VSSS ETPP PPPP PNEI NPPP HTME EEED DDWG EDTT EEAQ RRRM DEIS DHAK VLTL SDDL ERT |
遺伝子ID: | 1983 |
Uniprot: | P55010 |
セルラーロケーション: | |
計算された分子量: | 49kDa |
観察された分子量: | 55kDa |
同義語: | EIF5, EIF-5, EIF-5A |
バックグラウンド: |
UniProt Protein Function: | EIF5: eukaryotic translation initiation factor 5. Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex. |
UniProt Protein Details: | Protein type:Translation initiation; Translation Chromosomal Location of Human Ortholog: 14q32.32 Cellular Component: cytoplasm; cytosol; nucleus; plasma membrane Molecular Function:GTPase activity; protein binding; translation factor activity, nucleic acid binding Biological Process: regulation of translational initiation |
NCBI Summary: | Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010] |
UniProt Code: | P55010 |
NCBI GenInfo Identifier: | 27735202 |
NCBI Gene ID: | 1983 |
NCBI Accession: | P55010.2 |
UniProt Secondary Accession: | P55010,Q53XB3, Q9H5N2, Q9UG48, |
UniProt Related Accession: | P55010 |
Molecular Weight: | 49,223 Da |
NCBI Full Name: | Eukaryotic translation initiation factor 5 |
NCBI Synonym Full Names: | eukaryotic translation initiation factor 5 |
NCBI Official Symbol: | EIF5 |
NCBI Official Synonym Symbols: | EIF-5; EIF-5A |
NCBI Protein Information: | eukaryotic translation initiation factor 5 |
UniProt Protein Name: | Eukaryotic translation initiation factor 5 |
UniProt Gene Name: | EIF5 |
UniProt Entry Name: | IF5_HUMAN |
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