Anti-EIF4B Antibody (CAB5405)
- SKU:
- CAB5405
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-EIF4B Antibody |
抗体コード: | CAB5405 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF IP |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 352-611 of human EIF4B (NP_001408.2). |
申し込み: | WB IHC IF IP |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | A-549, HeLa, 293T, MCF7, 22Rv1 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 352-611 of human EIF4B (NP_001408.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SQST RAAS IFGG AKPV DTAA RERE VEER LQKE QEKL QRQL DEPK LERR PRER HPSW RSEE TQER ERSR TGSE SSQT GTST TSSR NARR RESE KSLE NETL NKEE DCHS PTSK PPKP DQPL KVMP APPP KENA WVKR SSNP PARS QSSD TEQQ SPTS GGGK VAPA QPSE EGPG RKDE NKVD GMNA PKGQ TGNS SRGP GDGG NRDH WKES DRKD GKKD QDSR SAPE PKKP EENP ASKF SSAS KYAA LSVD GEDE NEGE DYAE |
遺伝子ID: | 1975 |
Uniprot: | P23588 |
セルラーロケーション: | |
計算された分子量: | 64kDa/69kDa |
観察された分子量: | 80kDa |
同義語: | EIF4B, EIF-4B, PRO1843 |
バックグラウンド: |
UniProt Protein Function: | EIF4B: eukaryotic translation initiation factor 4B. Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. |
UniProt Protein Details: | Protein type:RNA-binding; Translation initiation; Translation Chromosomal Location of Human Ortholog: 12q13.13 Cellular Component: cytosol; eukaryotic translation initiation factor 4F complex; polysome Molecular Function:helicase activity; protein binding; ribosomal small subunit binding; RNA binding; RNA strand annealing activity; RNA strand-exchange activity Biological Process: formation of translation preinitiation complex; poly(A) tail shortening; regulation of translational initiation; translational initiation |
UniProt Code: | P23588 |
NCBI GenInfo Identifier: | 205371761 |
NCBI Gene ID: | 1975 |
NCBI Accession: | P23588.2 |
UniProt Secondary Accession: | P23588,Q4G0E3, Q53HQ2, Q6GPH5, Q6IB46, Q8WYK5, B4DS13 |
UniProt Related Accession: | P23588 |
Molecular Weight: | 64,805 Da |
NCBI Full Name: | Eukaryotic translation initiation factor 4B |
NCBI Synonym Full Names: | eukaryotic translation initiation factor 4B |
NCBI Official Symbol: | EIF4B |
NCBI Official Synonym Symbols: | EIF-4B; PRO1843 |
NCBI Protein Information: | eukaryotic translation initiation factor 4B |
UniProt Protein Name: | Eukaryotic translation initiation factor 4B |
Protein Family: | Eukaryotic translation initiation factor |
UniProt Gene Name: | EIF4B |
UniProt Entry Name: | IF4B_HUMAN |
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