Anti-EIF3K Antibody (CAB9969)
- SKU:
- CAB9969
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-EIF3K Antibody |
抗体コード: | CAB9969 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human EIF3K (NP_037366.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | SH-SY5Y, 293T, SGC-7901, HeLa, THP-1, Rat testis |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human EIF3K (NP_037366.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAMF EQMR ANVG KLLK GIDR YNPE NLAT LERY VETQ AKEN AYDL EANL AVLK LYQF NPAF FQTT VTAQ ILLK ALTN LPHT DFTL CKCM IDQA HQEE RPIR QILY LGDL LETC HFQA FWQA LDEN MDLL EGIT GFED SVRK FICH VVGI TYQH IDRW LLAE MLGD LSDS QLKV WMSK YGWS ADES GQIF ICSQ EESI KPKN IVEK IDFD SVSS IMAS SQ |
遺伝子ID: | 27335 |
Uniprot: | Q9UBQ5 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 24kDa/25kDa |
観察された分子量: | 25kDa |
同義語: | EIF3K, ARG134, EIF3-p28, EIF3S12, HSPC029, M9, MSTP001, PLAC-24, PLAC24, PRO1474, PTD001 |
バックグラウンド: |
UniProt Protein Function: | EIF3K: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Belongs to the eIF-3 subunit K family. |
UniProt Protein Details: | Protein type:Translation initiation; Translation Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: cytoplasm; cytosol; eukaryotic translation initiation factor 3 complex; membrane Molecular Function:protein binding; translation initiation factor activity Biological Process: translational initiation |
NCBI Summary: | The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9UBQ5 |
NCBI GenInfo Identifier: | 23396628 |
NCBI Gene ID: | 27335 |
NCBI Accession: | Q9UBQ5.1 |
UniProt Secondary Accession: | Q9UBQ5,Q96IQ0, Q9Y6D1, A8K0I9, B7ZAM9, |
UniProt Related Accession: | Q9UBQ5 |
Molecular Weight: | 24,484 Da |
NCBI Full Name: | Eukaryotic translation initiation factor 3 subunit K |
NCBI Synonym Full Names: | eukaryotic translation initiation factor 3 subunit K |
NCBI Official Symbol: | EIF3K |
NCBI Official Synonym Symbols: | M9; ARG134; PLAC24; PTD001; EIF3S12; HSPC029; MSTP001; PLAC-24; PRO1474; EIF3-p28 |
NCBI Protein Information: | eukaryotic translation initiation factor 3 subunit K |
UniProt Protein Name: | Eukaryotic translation initiation factor 3 subunit K |
UniProt Synonym Protein Names: | Eukaryotic translation initiation factor 3 subunit 12 |
UniProt Gene Name: | EIF3K |
UniProt Entry Name: | EIF3K_HUMAN |
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