Anti-DEGS1 Antibody (CAB12648)
- SKU:
- CAB12648
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-DEGS1 Antibody |
抗体コード: | CAB12648 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 234-323 of human DEGS1 (NP_003667.1). |
申し込み: | WB |
推奨希釈: | WB 1:1000 - 1:3000 |
反応性: | Human |
ポジティブサンプル: | HeLa, A-549, 293T |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 234-323 of human DEGS1 (NP_003667.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | YMFL KGHE TYSY YGPL NLLT FNVG YHNE HHDF PNIP GKSL PLVR KIAA EYYD NLPH YNSW IKVL YDFV MDDT ISPY SRMK RHQK GEMV LE |
遺伝子ID: | 8560 |
Uniprot: | O15121 |
セルラーロケーション: | Endoplasmic reticulum membrane, Lipid-anchor, Membrane, Mitochondrion, Multi-pass membrane protein |
計算された分子量: | 37kDa |
観察された分子量: | 38kDa |
同義語: | DEGS1, DEGS, DEGS-1, DES1, Des-1, FADS7, MIG15, MLD |
バックグラウンド: | This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. |
UniProt Protein Function: | DEGS1: Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). Belongs to the fatty acid desaturase family. DEGS subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Oxidoreductase; EC 1.14.-.-; Lipid Metabolism - sphingolipid Chromosomal Location of Human Ortholog: 1q42.11 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to plasma membrane; membrane Molecular Function:electron carrier activity; sphingolipid delta-4 desaturase activity Biological Process: sphingolipid biosynthetic process; unsaturated fatty acid biosynthetic process |
NCBI Summary: | This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010] |
UniProt Code: | O15121 |
NCBI GenInfo Identifier: | 74739483 |
NCBI Gene ID: | 8560 |
NCBI Accession: | O15121.1 |
UniProt Related Accession: | O15121 |
Molecular Weight: | 37,866 Da |
NCBI Full Name: | Sphingolipid delta(4)-desaturase DES1 |
NCBI Synonym Full Names: | delta 4-desaturase, sphingolipid 1 |
NCBI Official Symbol: | DEGS1 |
NCBI Official Synonym Symbols: | MLD; DEGS; DES1; Des-1; FADS7; MIG15; DEGS-1 |
NCBI Protein Information: | sphingolipid delta(4)-desaturase DES1 |
UniProt Protein Name: | Sphingolipid delta(4)-desaturase DES1 |
UniProt Synonym Protein Names: | Cell migration-inducing gene 15 protein; Degenerative spermatocyte homolog 1; Membrane lipid desaturase |
UniProt Gene Name: | DEGS1 |
UniProt Entry Name: | DEGS1_HUMAN |
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