Anti-DAP Antibody (CAB6150)
- SKU:
- CAB6150
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
抗体名: | Anti-DAP Antibody |
抗体コード: | CAB6150 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human DAP (NP_004385.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, NIH/3T3, 293T, Rat testis |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human DAP (NP_004385.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MSSP PEGK LETK AGHP PAVK AGGM RIVQ KHPH TGDT KEEK DKDD QEWE SPSP PKPT VFIS GVIA RGDK DFPP AAAQ VAHQ KPHA SMDK HPSP RTQH IQQP RK |
遺伝子ID: | 1611 |
Uniprot: | P51397 |
セルラーロケーション: | |
計算された分子量: | 11kDa |
観察された分子量: | 17kDa |
同義語: | DAP |
バックグラウンド: | This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
UniProt Protein Function: | DAP: a 15 kDa, proline rich protein that possesses one SH3 binding motif. Negatively regulates autophagy and is involved in mediating interferon-gamma-induced cell death. Localizes in the cytoplasm, but the detailed mechanism of its proapoptotic function is unclear. |
UniProt Protein Details: | Protein type:Autophagy Chromosomal Location of Human Ortholog: 5p15.2 Biological Process: apoptosis; caspase activation; cellular response to amino acid starvation; inhibition of NF-kappaB transcription factor; negative regulation of autophagy; negative regulation of transcription, DNA-dependent |
NCBI Summary: | This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
UniProt Code: | P51397 |
NCBI GenInfo Identifier: | 1706298 |
NCBI Gene ID: | 1611 |
NCBI Accession: | P51397.3 |
UniProt Secondary Accession: | P51397,Q6FGC3, Q9BUC9, |
UniProt Related Accession: | P51397 |
Molecular Weight: | 11,165 Da |
NCBI Full Name: | Death-associated protein 1 |
NCBI Synonym Full Names: | death associated protein |
NCBI Official Symbol: | DAP |
NCBI Protein Information: | death-associated protein 1 |
UniProt Protein Name: | Death-associated protein 1 |
Protein Family: | Dapper |
UniProt Gene Name: | DAP |
UniProt Entry Name: | DAP1_HUMAN |
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