Anti-CTPS1 Antibody (CAB3817)
- SKU:
- CAB3817
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
抗体名: | Anti-CTPS1 Antibody |
抗体コード: | CAB3817 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 402-591 of human CTPS1 (NP_001896.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | Raji, HeLa, 22Rv1, Jurkat, Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 402-591 of human CTPS1 (NP_001896.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MQLA VVEF SRNV LGWQ DANS TEFD PTTS HPVV VDMP EHNP GQMG GTMR LGKR RTLF QTKN SVMR KLYG DADY LEER HRHR FEVN PVWK KCLE EQGL KFVG QDVE GERM EIVE LEDH PFFV GVQY HPEF LSRP IKPS PPYF GLLL ASVG RLSH YLQK GCRL SPRD TYSD RSGS SSPD SEIT ELKF PSIN HD |
遺伝子ID: | 1503 |
Uniprot: | P17812 |
セルラーロケーション: | |
計算された分子量: | 41kDa/66kDa |
観察された分子量: | 80kDa |
同義語: | CTPS1, CTPS, GATD5, IMD24 |
バックグラウンド: | This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | CTPS: the enzyme cytidine-5-prime-triphosphate synthetase converts UTP to CTP. Important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; EC 6.3.4.2; Nucleotide Metabolism - pyrimidine; Ligase Chromosomal Location of Human Ortholog: 1p34.1 Cellular Component: membrane; cytosol Molecular Function:CTP synthase activity; ATP binding Biological Process: T cell proliferation; B cell proliferation; response to drug; CTP biosynthetic process; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside and nucleotide interconversion; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; glutamine metabolic process Disease: Immunodeficiency 24 |
NCBI Summary: | This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
UniProt Code: | P17812 |
NCBI GenInfo Identifier: | 20981706 |
NCBI Gene ID: | 1503 |
NCBI Accession: | P17812.2 |
UniProt Related Accession: | P17812 |
Molecular Weight: | ~ 67kDa |
NCBI Full Name: | CTP synthase 1 |
NCBI Synonym Full Names: | CTP synthase 1 |
NCBI Official Symbol: | CTPS1 |
NCBI Official Synonym Symbols: | CTPS; GATD5; IMD24 |
NCBI Protein Information: | CTP synthase 1 |
UniProt Protein Name: | CTP synthase 1 |
UniProt Synonym Protein Names: | CTP synthetase 1; UTP--ammonia ligase 1 |
UniProt Gene Name: | CTPS1 |
UniProt Entry Name: | PYRG1_HUMAN |
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