Anti-CRABP2 Antibody (CAB6119)
- SKU:
- CAB6119
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-CRABP2 Antibody |
抗体コード: | CAB6119 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-94 of human CRABP2 (NP_001869.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | MCF7, SW480, A-431, 22Rv1, HT-29, 293T, Mouse brain, Mouse uterus |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-94 of human CRABP2 (NP_001869.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | VLGV NVML RKIA VAAA SKPA VEIK QEGD TFYI KTST TVRT TEIN FKVG EEFE EQTV DGRP CKSL VKWE SENK M |
遺伝子ID: | 1382 |
Uniprot: | P29373 |
セルラーロケーション: | Cytoplasm, Endoplasmic reticulum, Nucleus |
計算された分子量: | 15kDa |
観察された分子量: | 15kDa |
同義語: | CRABP2, CRABP-II, RBP6 |
バックグラウンド: | This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
UniProt Protein Function: | CRABP2: Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 1q21.3 Cellular Component: nucleoplasm; endoplasmic reticulum; cytoplasm; cytosol Molecular Function:retinoid binding; retinoic acid binding; transporter activity; retinal binding; retinol binding Biological Process: embryonic forelimb morphogenesis; epidermis development; regulation of transcription, DNA-dependent; retinoic acid metabolic process; signal transduction; transmembrane transport |
NCBI Summary: | This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2010] |
UniProt Code: | P29373 |
NCBI GenInfo Identifier: | 132401 |
NCBI Gene ID: | 1382 |
NCBI Accession: | P29373.2 |
UniProt Secondary Accession: | P29373,Q6ICN6, B2R4Z8, D3DVC5, F1T098, |
UniProt Related Accession: | P29373 |
Molecular Weight: | 138 |
NCBI Full Name: | Cellular retinoic acid-binding protein 2 |
NCBI Synonym Full Names: | cellular retinoic acid binding protein 2 |
NCBI Official Symbol: | CRABP2 |
NCBI Official Synonym Symbols: | RBP6; CRABP-II |
NCBI Protein Information: | cellular retinoic acid-binding protein 2; cellular retinoic acid-binding protein II |
UniProt Protein Name: | Cellular retinoic acid-binding protein 2 |
UniProt Synonym Protein Names: | Cellular retinoic acid-binding protein II; CRABP-II |
Protein Family: | Cellular retinoic acid-binding protein |
UniProt Gene Name: | CRABP2 |
UniProt Entry Name: | RABP2_HUMAN |
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