Anti-CHST1 Antibody (CAB13057)
- SKU:
- CAB13057
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-CHST1 Antibody |
抗体コード: | CAB13057 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-411 of human CHST1 (NP_003645.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:1000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse liver, Mouse kidney, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-411 of human CHST1 (NP_003645.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | HILI LATT RSGS SFVG QLFN QHLD VFYL FEPL YHVQ NTLI PRFT QGKS PADR RVML GASR DLLR SLYD CDLY FLEN YIKP PPVN HTTD RIFR RGAS RVLC SRPV CDPP GPAD LVLE EGDC VRKC GLLN LTVA AEAC RERS HVAI KTVR VPEV NDLR ALVE DPRL NLKV IQLV RDPR GILA SRSE TFRD TYRL WRLW YGTG RKPY NLDV TQLT TVCE DFSN SVST GLMR PPWL KGKY MLVR YEDL ARNP MKKT EEIY GFLG IPLD SHVA RWIQ NNTR GDPT LGKH KYGT VRNS AATA EKWR FRLS YDIV AFAQ NACQ QVLA QLGY KIAA SEEE LKNP SVSL VEER DFRP FS |
遺伝子ID: | 8534 |
Uniprot: | O43916 |
セルラーロケーション: | Golgi apparatus membrane, Single-pass type II membrane protein |
計算された分子量: | 46kDa |
観察された分子量: | 47kDa |
同義語: | CHST1, C6ST, GST-1, KS6ST, KSGal6ST, KSST |
バックグラウンド: | This locus encodes a member of the keratin sulfotransferase family of proteins. The encoded enzyme catalyzes the sulfation of the proteoglycan keratin. |
UniProt Protein Function: | CHST1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of galactose (Gal) residues of keratan. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. May function in the sulfation of sialyl N- acetyllactosamine oligosaccharide chains attached to glycoproteins. Participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily. |
UniProt Protein Details: | Protein type:EC 2.8.2.21; Membrane protein, integral; Glycan Metabolism - keratan sulfate biosynthesis; Transferase Chromosomal Location of Human Ortholog: 11p11.2 Cellular Component: Golgi membrane Molecular Function:keratan sulfotransferase activity; N-acetylglucosamine 6-O-sulfotransferase activity; sulfotransferase activity Biological Process: galactose metabolic process; keratan sulfate biosynthetic process; keratan sulfate metabolic process; polysaccharide metabolic process; sulfur metabolic process |
NCBI Summary: | This locus encodes a member of the keratin sulfotransferase family of proteins. The encoded enzyme catalyzes the sulfation of the proteoglycan keratin. [provided by RefSeq, Aug 2011] |
UniProt Code: | O43916 |
NCBI GenInfo Identifier: | 61211700 |
NCBI Gene ID: | 8534 |
NCBI Accession: | O43916.1 |
UniProt Secondary Accession: | O43916,D3DQP2, |
UniProt Related Accession: | O43916 |
Molecular Weight: | 46,715 Da |
NCBI Full Name: | Carbohydrate sulfotransferase 1 |
NCBI Synonym Full Names: | carbohydrate sulfotransferase 1 |
NCBI Official Symbol: | CHST1 |
NCBI Official Synonym Symbols: | C6ST; KSST; GST-1; KS6ST; KSGal6ST |
NCBI Protein Information: | carbohydrate sulfotransferase 1 |
UniProt Protein Name: | Carbohydrate sulfotransferase 1 |
UniProt Synonym Protein Names: | Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1; GST-1; Keratan sulfate Gal-6 sulfotransferase; KS6ST; KSGal6ST; KSST |
Protein Family: | Carbohydrate sulfotransferase |
UniProt Gene Name: | CHST1 |
UniProt Entry Name: | CHST1_HUMAN |
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