Anti-CETP Antibody (CAB1355)
- SKU:
- CAB1355
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
抗体名: | Anti-CETP Antibody |
抗体コード: | CAB1355 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-493 of human CETP (NP_000069.2). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | A-549, HepG2, A375, Mouse liver, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-493 of human CETP (NP_000069.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LMLS LMGD EFKA VLET WGFN TNQE IFQE VVGG FPSQ AQVT VHCL KMPK ISCQ NKGV VVNS SVMV KFLF PRPD QQHS VAYT FEED IVTT VQAS YSKK KLFL SLLD FQIT PKTV SNLT ESSS ESVQ SFLQ SMIT AVGI PEVM SRLE VVFT ALMN SKGV SLFD IINP EIIT RDGF LLLQ MDFG FPEH LLVD FLQS LS |
遺伝子ID: | 1071 |
Uniprot: | P11597 |
セルラーロケーション: | Secreted, extracellular space |
計算された分子量: | 47kDa/54kDa |
観察された分子量: | 75kDa |
同義語: | CETP, BPIFF, HDLCQ10 |
バックグラウンド: | The protein encoded by this gene is found in plasma, where it is involved in the transfer of cholesteryl ester from high density lipoprotein (HDL) to other lipoproteins. Defects in this gene are a cause of hyperalphalipoproteinemia 1 (HALP1). Two transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | CETP: Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol. Defects in CETP are the cause of hyperalphalipoproteinemia type 1 (HALP1). Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL). Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Lipid-binding; Secreted; Secreted, signal peptide; Vesicle Chromosomal Location of Human Ortholog: 16q21 Cellular Component: extracellular space; extracellular region; vesicle Molecular Function:lipid transporter activity; phospholipid transporter activity; cholesterol transporter activity; cholesterol binding; phosphatidylcholine binding; lipid binding; triglyceride binding Biological Process: cholesterol metabolic process; receptor-mediated endocytosis; cholesterol transport; lipid homeostasis; lipoprotein metabolic process; lipid transport; phosphatidylcholine metabolic process; cholesterol homeostasis; reverse cholesterol transport; triacylglycerol metabolic process; phospholipid transport; triacylglycerol transport; transmembrane transport; phospholipid homeostasis Disease: Hyperalphalipoproteinemia 1 |
NCBI Summary: | The protein encoded by this gene is found in plasma, where it is involved in the transfer of cholesteryl ester from high density lipoprotein (HDL) to other lipoproteins. Defects in this gene are a cause of hyperalphalipoproteinemia 1 (HALP1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013] |
UniProt Code: | P11597 |
NCBI GenInfo Identifier: | 71153497 |
NCBI Gene ID: | 1071 |
NCBI Accession: | P11597.2 |
UniProt Secondary Accession: | P11597,Q13987, Q13988, Q53YZ1, |
UniProt Related Accession: | P11597 |
Molecular Weight: | 47,787 Da |
NCBI Full Name: | Cholesteryl ester transfer protein |
NCBI Synonym Full Names: | cholesteryl ester transfer protein, plasma |
NCBI Official Symbol: | CETP |
NCBI Official Synonym Symbols: | BPIFF; HDLCQ10 |
NCBI Protein Information: | cholesteryl ester transfer protein; lipid transfer protein I; BPI fold containing family F |
UniProt Protein Name: | Cholesteryl ester transfer protein |
UniProt Synonym Protein Names: | Lipid transfer protein I |
Protein Family: | Cholesteryl ester transfer protein |
UniProt Gene Name: | CETP |
UniProt Entry Name: | CETP_HUMAN |