Anti-CEACAM6 Antibody (CAB8440)
- SKU:
- CAB8440
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
抗体名: | Anti-CEACAM6 Antibody |
抗体コード: | CAB8440 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-320 of human CEACAM6 (NP_002474.4). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | A-549, Raji, HeLa, Mouse lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-320 of human CEACAM6 (NP_002474.4). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LTLL SVKR NDAG SYEC EIQN PASA NRSD PVTL NVLY GPDV PTIS PSKA NYRP GENL NLSC HAAS NPPA QYSW FING TFQQ STQE LFIP NITV NNSG SYMC QAHN SATG LNRT TVTM ITVS G |
遺伝子ID: | 4680 |
Uniprot: | P40199 |
セルラーロケーション: | Cell membrane, GPI-anchor, Lipid-anchor |
計算された分子量: | 37kDa |
観察された分子量: | 110kDa |
同義語: | CEACAM6, CD66c, CEAL, NCA |
バックグラウンド: | This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. |
UniProt Protein Function: | CEACAM6: Belongs to the immunoglobulin superfamily. CEA family |
UniProt Protein Details: | Protein type:Membrane protein, GPI anchor; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: extracellular space; integral to plasma membrane; plasma membrane Molecular Function:protein binding Biological Process: cell-cell signaling; leukocyte migration; signal transduction |
NCBI Summary: | This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014] |
UniProt Code: | P40199 |
NCBI GenInfo Identifier: | 296439410 |
NCBI Gene ID: | 4680 |
NCBI Accession: | P40199.3 |
UniProt Secondary Accession: | P40199,Q13774, Q14920, Q53XP7, |
UniProt Related Accession: | P40199 |
Molecular Weight: | 37,195 Da |
NCBI Full Name: | Carcinoembryonic antigen-related cell adhesion molecule 6 |
NCBI Synonym Full Names: | carcinoembryonic antigen related cell adhesion molecule 6 |
NCBI Official Symbol: | CEACAM6 |
NCBI Official Synonym Symbols: | NCA; CEAL; CD66c |
NCBI Protein Information: | carcinoembryonic antigen-related cell adhesion molecule 6 |
UniProt Protein Name: | Carcinoembryonic antigen-related cell adhesion molecule 6 |
UniProt Synonym Protein Names: | Non-specific crossreacting antigen; Normal cross-reacting antigen; CD_antigen: CD66c |
Protein Family: | Carcinoembryonic antigen-related cell adhesion molecule |
UniProt Gene Name: | CEACAM6 |
UniProt Entry Name: | CEAM6_HUMAN |
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