Anti-CDYL Antibody (CAB6258)
- SKU:
- CAB6258
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
抗体名: | Anti-CDYL Antibody |
抗体コード: | CAB6258 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 245-544 of human CDYL (NP_004815.3). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Rat |
ポジティブサンプル: | U-251MG |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 245-544 of human CDYL (NP_004815.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | TNIQ TSVT GVTA SKRK FIDD RRDQ PFDK RLRF SVRQ TESA YRYR DIVV RKQD GFTH ILLS TKSS ENNS LNPE VMRE VQSA LSTA AADD SKLV LLSA VGSV FCCG LDFI YFIR RLTD DRKR ESTK MAEA IRNF VNTF IQFK KPII VAVN GPAI GLGA SILP LCDV VWAN EKAW FQTP YTTF GQSP DGCS TVMF PKIM GGAS ANEM LLSG RKLT AQEA CGKG LVSQ VFWP GTFT QEVM VRIK ELAS CNPV VLEE SKAL VRCN MKME LEQA NERE CEVL KKIW GSAQ GMDS MLKY LQRK IDEF |
遺伝子ID: | 9425 |
Uniprot: | Q9Y232 |
セルラーロケーション: | Nucleus |
計算された分子量: | 34kDa/45kDa/60kDa/66kDa |
観察された分子量: | 75kDa |
同義語: | CDYL, CDYL1 |
バックグラウンド: | Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene. |
UniProt Protein Function: | CDYL: Acts as repressor of transcription. Has histone acetyltransferase activity, with a preference for histone H4. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Acetyltransferase; EC 2.3.1.48; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 6p25.1 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; histone acetyltransferase activity; transcription corepressor activity; methylated histone residue binding Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; spermatogenesis; histone acetylation |
NCBI Summary: | Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y232 |
NCBI GenInfo Identifier: | 150421527 |
NCBI Gene ID: | 9425 |
NCBI Accession: | Q9Y232.2 |
UniProt Secondary Accession: | Q9Y232,Q0VDG7, Q32NC5, Q5VX99, Q6P7T5, Q9BWZ2, Q9Y424 A8K6D6, B4DLG4, |
UniProt Related Accession: | Q9Y232 |
Molecular Weight: | 598 |
NCBI Full Name: | Chromodomain Y-like protein |
NCBI Synonym Full Names: | chromodomain protein, Y-like |
NCBI Official Symbol: | CDYL |
NCBI Official Synonym Symbols: | CDYL1 |
NCBI Protein Information: | chromodomain Y-like protein; CDY-like, autosomal; testis-specific chromodomain Y-like protein |
UniProt Protein Name: | Chromodomain Y-like protein |
Protein Family: | Chromodomain Y-like protein |
UniProt Gene Name: | CDYL |
UniProt Entry Name: | CDYL1_HUMAN |
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