Anti-CD69 Antibody (CAB2045)
- SKU:
- CAB2045
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-CD69 Antibody |
抗体コード: | CAB2045 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-199 of human CD69 (NP_001772.1). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-937, Mouse lung, Mouse spleen, Rat lung, Rat spleen |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-199 of human CD69 (NP_001772.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SVGQ YNCP GQYT FSMP SDSH VSSC SEDW VGYQ RKCY FIST VKRS WTSA QNAC SEHG ATLA VIDS EKDM NFLK RYAG REEH WVGL KKEP GHPW KWSN GKEF NNWF NVTG SDKC VFLK NTEV SSME CEKN LYWI CNKP YK |
遺伝子ID: | 969 |
Uniprot: | Q07108 |
セルラーロケーション: | Membrane, Single-pass type II membrane protein |
計算された分子量: | 22kDa |
観察された分子量: | 25-45KDa |
同義語: | CD69, AIM, BL-AC/P26, CLEC2C, EA1, GP32/28, MLR-3 |
バックグラウンド: | This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. |
UniProt Protein Function: | Function: Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. |
UniProt Protein Details: | Subunit structure: Homodimer; disulfide-linked. Ref.6 Ref.7 Ref.8 Subcellular location: Membrane; Single-pass type II membrane protein. Tissue specificity: Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets. Developmental stage: Earliest inducible cell surface glycoprotein acquired during lymphoid activation. Induction: By antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes. By interaction of IL-2 with the p75 IL-2R on the surface of NK cells. Post-translational modification: Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes. Sequence similarities: Contains 1 C-type lectin domain. |
NCBI Summary: | This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011] |
UniProt Code: | Q07108 |
NCBI GenInfo Identifier: | 584906 |
NCBI Gene ID: | 969 |
NCBI Accession: | Q07108.1 |
UniProt Related Accession: | Q07108 |
Molecular Weight: | 22,559 Da |
NCBI Full Name: | Early activation antigen CD69 |
NCBI Synonym Full Names: | CD69 molecule |
NCBI Official Symbol: | CD69 |
NCBI Official Synonym Symbols: | AIM; EA1; MLR-3; CLEC2C; GP32/28; BL-AC/P26 |
NCBI Protein Information: | early activation antigen CD69; leukocyte surface antigen Leu-23; early T-cell activation antigen p60; early lymphocyte activation antigen; activation inducer molecule (AIM/CD69); C-type lectin domain family 2, member C; CD69 antigen (p60, early T-cell act |
UniProt Protein Name: | Early activation antigen CD69 |
UniProt Synonym Protein Names: | Activation inducer molecule; AIM; BL-AC/P26; C-type lectin domain family 2 member C; EA1; Early T-cell activation antigen p60; GP32/28; Leukocyte surface antigen Leu-23; MLR-3 |
UniProt Gene Name: | CD69 |
UniProt Entry Name: | CD69_HUMAN |
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