Anti-CCDC50 Antibody (CAB17836)
- SKU:
- CAB17836
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-CCDC50 Antibody |
抗体コード: | CAB17836 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-147 of human CCDC50 (NP_777568.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | LO2, 293T, U-87MG, Mouse lung, Mouse brain, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-147 of human CCDC50 (NP_777568.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | KLPG VKEV CRDF AVLE DHTL AHSL QEQE IEHH LASN VQRN RLVQ HDLQ VAKQ LQEE DLKA QAQL QKRY KDLE QQDC EIAQ EIQE KLAI EAER RRIQ EKKD EDIA RLLQ EKEL QEEK KRKK HFPE FPAT RAYA DSYY YE |
遺伝子ID: | 152137 |
Uniprot: | Q8IVM0 |
セルラーロケーション: | |
計算された分子量: | 35kDa/56kDa |
観察された分子量: | 36kDa |
同義語: | C3orf6, DFNA44, YMER, CCDC50 |
バックグラウンド: | This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
UniProt Protein Function: | Involved in EGFR signaling. |
NCBI Summary: | This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
UniProt Code: | Q8IVM0 |
NCBI GenInfo Identifier: | 73619722 |
NCBI Gene ID: | 152137 |
NCBI Accession: | Q8IVM0.1 |
UniProt Secondary Accession: | Q8IVM0,Q86VH7, |
UniProt Related Accession: | Q8IVM0 |
Molecular Weight: | 56,340 Da |
NCBI Full Name: | Coiled-coil domain-containing protein 50 |
NCBI Synonym Full Names: | coiled-coil domain containing 50 |
NCBI Official Symbol: | CCDC50 |
NCBI Official Synonym Symbols: | YMER; C3orf6; DFNA44 |
NCBI Protein Information: | coiled-coil domain-containing protein 50 |
UniProt Protein Name: | Coiled-coil domain-containing protein 50 |
UniProt Synonym Protein Names: | Protein Ymer |
Protein Family: | Coiled-coil domain-containing protein |
UniProt Gene Name: | CCDC50 |
UniProt Entry Name: | CCD50_HUMAN |