Anti-CAPRIN1 Antibody (CAB7910)
- SKU:
- CAB7910
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
抗体名: | Anti-CAPRIN1 Antibody |
抗体コード: | CAB7910 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant protein of human CAPRIN1 |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HL-60, HeLa, Jurkat |
免疫原: | Recombinant protein of human CAPRIN1 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 4076 |
Uniprot: | Q14444 |
セルラーロケーション: | Cell projection, Cytoplasm, cytosol, dendrite |
計算された分子量: | 76kDa/78kDa |
観察された分子量: | 120kDa |
同義語: | CAPRIN1, GPIAP1, GPIP137, GRIP137, M11S1, RNG105, p137GPI, caprin-1 |
バックグラウンド: | CAPRIN1(Caprin-1) is a cytoplasmic phosphoprotein which may regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Its levels, except in the brain, are tightly correlated with cellular proliferation. Suppression of expression of human Caprin-1 resulted in slowing of the proliferation rate, which suggests its essential for normal cellular proliferation. |
UniProt Protein Function: | CAPRIN1: May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Belongs to the caprin family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA-binding; Cell surface Chromosomal Location of Human Ortholog: 11p13 Cellular Component: membrane; stress granule; integral to plasma membrane; cytoplasm; dendrite; cytosol Molecular Function:RNA binding Biological Process: negative regulation of translation; positive regulation of dendrite morphogenesis |
UniProt Code: | Q14444 |
NCBI GenInfo Identifier: | 182676426 |
NCBI Gene ID: | 4076 |
NCBI Accession: | Q14444.2 |
UniProt Secondary Accession: | Q14444,Q15074, Q6IMN4, Q6IMN7, Q9BV09, A6NMY7, D3DR06 |
UniProt Related Accession: | Q14444 |
Molecular Weight: | 709 |
NCBI Full Name: | Caprin-1 |
NCBI Synonym Full Names: | cell cycle associated protein 1 |
NCBI Official Symbol: | CAPRIN1 |
NCBI Official Synonym Symbols: | M11S1; GPIAP1; RNG105; GPIP137; GRIP137; p137GPI |
NCBI Protein Information: | caprin-1; GPI-p137; caprin 1; RNA granule protein 105; GPI-anchored protein p137; GPI-anchored membrane protein 1; cell cycle-associated protein 1; activation/proliferation-associated protein 1; membrane component chromosome 11 surface marker 1; membrane |
UniProt Protein Name: | Caprin-1 |
UniProt Synonym Protein Names: | Cell cycle-associated protein 1; Cytoplasmic activation- and proliferation-associated protein 1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; p137GPI; Membrane component chromosome 11 surface marker 1; RNA granule protein 105 |
Protein Family: | Caprin |
UniProt Gene Name: | CAPRIN1 |
UniProt Entry Name: | CAPR1_HUMAN |
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