Anti-C8orf4 Antibody (CAB6241)
- SKU:
- CAB6241
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
抗体名: | Anti-C8orf4 Antibody |
抗体コード: | CAB6241 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human C8orf4 (NP_064515.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human C8orf4 (NP_064515.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MKAK RSHQ AIIM STSL RVSP SIHG YHFD TASR KKAV GNIF ENTD QESL ERLF RNSG DKKA EERA KIIF AIDQ DVEE KTRA LMAL KKRT KDKL FQFL KLRK YSIK VH |
遺伝子ID: | 56892 |
Uniprot: | Q9NR00 |
セルラーロケーション: | Cytoplasm, Nucleus, Nucleus speckle, nucleolus |
計算された分子量: | 12kDa |
観察された分子量: | Refer to figures |
同義語: | C8orf4, TC-1, TC1 |
バックグラウンド: | This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. |
UniProt Protein Function: | C8orf4: May decrease apoptosis. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 8p11.2 Biological Process: apoptosis |
NCBI Summary: | This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011] |
UniProt Code: | Q9NR00 |
NCBI GenInfo Identifier: | 296434443 |
NCBI Gene ID: | 56892 |
NCBI Accession: | Q9NR00.2 |
UniProt Related Accession: | Q9NR00 |
Molecular Weight: | 106 |
NCBI Full Name: | Uncharacterized protein C8orf4 |
NCBI Synonym Full Names: | chromosome 8 open reading frame 4 |
NCBI Official Symbol: | C8orf4 |
NCBI Official Synonym Symbols: | TC1; TC-1 |
NCBI Protein Information: | uncharacterized protein C8orf4; human thyroid cancer 1; thyroid cancer protein 1 |
UniProt Protein Name: | Uncharacterized protein C8orf4 |
UniProt Synonym Protein Names: | Thyroid cancer protein 1; TC-1 |
Protein Family: | Protein |
UniProt Gene Name: | C8orf4 |
UniProt Entry Name: | CH004_HUMAN |
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