Anti-BCAT2 Antibody (CAB7426)
- SKU:
- CAB7426
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-BCAT2 Antibody |
抗体コード: | CAB7426 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human BCAT2 (NP_001181.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | MCF7, Jurkat, Mouse brain, Rat kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human BCAT2 (NP_001181.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LLCG PRRY ASSS FKAA DLQL EMTQ KPHK KPGP GEPL VFGK TFTD HMLM VEWN DKGW GQPR IQPF QNLT LHPA SSSL HYSL QLFE GMKA FKGK DQQV RLFR PWLN MDRM LRSA MRLC LPSF DKLE LLEC IRRL IEVD KDWV PDAA GTSL YVRP VLIG NEPS LGVS QPTR ALLF VILC PVGA Y |
遺伝子ID: | 587 |
Uniprot: | O15382 |
セルラーロケーション: | Cytoplasm, Mitochondrion |
計算された分子量: | 33kDa/44kDa |
観察された分子量: | 39KDa |
同義語: | BCAT2, BCAM, BCATM, BCT2, PP18 |
バックグラウンド: | This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | BCAT2: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. Homodimer. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; EC 2.6.1.42; Mitochondrial; Transferase; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis Chromosomal Location of Human Ortholog: 19q13 Cellular Component: mitochondrion; mitochondrial matrix Molecular Function:branched-chain-amino-acid transaminase activity Biological Process: valine metabolic process; branched chain family amino acid catabolic process; leucine metabolic process; branched chain family amino acid biosynthetic process; isoleucine catabolic process |
NCBI Summary: | This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
UniProt Code: | O15382 |
NCBI GenInfo Identifier: | 20455470 |
NCBI Gene ID: | 587 |
NCBI Accession: | O15382.2 |
UniProt Secondary Accession: | O15382,O00269, Q96KG1, Q9BTB6, Q9BUU6, B2RB87, |
UniProt Related Accession: | O15382 |
Molecular Weight: | 33,777 Da |
NCBI Full Name: | Branched-chain-amino-acid aminotransferase, mitochondrial |
NCBI Synonym Full Names: | branched chain amino-acid transaminase 2, mitochondrial |
NCBI Official Symbol: | BCAT2 |
NCBI Official Synonym Symbols: | BCAM; BCT2; PP18; BCATM |
NCBI Protein Information: | branched-chain-amino-acid aminotransferase, mitochondrial; placental protein 18; branched chain aminotransferase 2, mitochondrial |
UniProt Protein Name: | Branched-chain-amino-acid aminotransferase, mitochondrial |
UniProt Synonym Protein Names: | Placental protein 18; PP18 |
UniProt Gene Name: | BCAT2 |
UniProt Entry Name: | BCAT2_HUMAN |
View AllClose