Anti-BAF250 Antibody (CAB7607)
- SKU:
- CAB7607
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-BAF250 Antibody |
抗体コード: | CAB7607 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1300-1400 of mouse BAF250 (NP_001074288.1). |
申し込み: | IF |
推奨希釈: | IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1300-1400 of mouse BAF250 (NP_001074288.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | NMGT GAPQ PNLM PSTP DSGM YSPS RYPP QQQQ QQQQ QHDS YGNQ FSTQ GTPS SSPF PSQQ TTMY QQQQ QNYK RPMD GTYG PPAK RHEG EMYS VPYS AGQG Q |
遺伝子ID: | 93760 |
Uniprot: | |
セルラーロケーション: | Nucleus |
計算された分子量: | 206kDa/218kDa/242kDa |
観察された分子量: |
同義語: | ARID1A, B120, BAF250, BAF250a, BM029, C1orf4, CSS2, ELD, MRD14, OSA1, P270, SMARCF1, hELD, hOSA1 |
バックグラウンド: | This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. |