Anti-ATP5H Antibody (CAB4425)
- SKU:
- CAB4425
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ATP5H
- Synonyms:
- ATPQ
Frequently bought together:
Description
| 抗体名: | ATP5H Rabbit pAb |
| 抗体コード: | CAB4425 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | ATP5H, ATPQ |
| 申し込み: | WB, IHC, IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human ATP5H (NP_006347.1). |
| 申し込み: | WB, IHC, IF |
| 推奨される希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | COS-7, HepG2, U-251MG, BxPC-3, HeLa, Mouse kidney, Mouse thymus, Mouse brain, Rat spinal cord |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human ATP5H (NP_006347.1). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAGR KLAL KTID WVAF AEII PQNQ KAIA SSLK SWNE TLTS RLAA LPEN PPAI DWAY YKAN VAKA GLVD DFEK KFNA LKVP VPED KYTA QVDA EEKE DVKS CAEW VSLS KARI VEYE KEME KMKN LIPF DQMT IEDL NEAF PETK LDKK KYPY WPHQ PIEN L |
| 遺伝子ID: | 10476 |
| Uniprot: | O75947 |
| セルラーロケーション: | Mitochondrion, Mitochondrion inner membrane |
| 計算された分子量: | 15kDa/18kDa |
| 観察された分子量: | 18kDa |
| UniProt Protein Function: | ATP5H: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Belongs to the ATPase d subunit family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Mitochondrial; Energy Metabolism - oxidative phosphorylation; EC 3.6.3.14 Chromosomal Location of Human Ortholog: 17q25 Cellular Component: nucleoplasm; mitochondrion; cytoplasm; mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex Molecular Function:ATPase activity; transmembrane transporter activity; hydrogen ion transmembrane transporter activity Biological Process: cellular metabolic process; mitochondrial ATP synthesis coupled proton transport |
| NCBI Summary: | Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the d subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. In addition, three pseudogenes are located on chromosomes 9, 12 and 15. [provided by RefSeq, Jun 2010] |
| UniProt Code: | O75947 |
| NCBI GenInfo Identifier: | 6831494 |
| NCBI Gene ID: | 10476 |
| NCBI Accession: | O75947.3 |
| UniProt Secondary Accession: | O75947,Q9H3J4, B2R5L6, |
| UniProt Related Accession: | O75947 |
| Molecular Weight: | Observed MW 18kDaCalculated MW 15kDa/18kDa |
| NCBI Full Name: | ATP synthase subunit d, mitochondrial |
| NCBI Synonym Full Names: | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d |
| NCBI Official Symbol: | ATP5H |
| NCBI Official Synonym Symbols: | ATPQ |
| NCBI Protein Information: | ATP synthase subunit d, mitochondrial; My032 protein; ATPase subunit d; ATP synthase D chain, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1F0, subunit d; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d |
| UniProt Protein Name: | ATP synthase subunit d, mitochondrial |
| UniProt Gene Name: | ATP5H |
| UniProt Entry Name: | ATP5H_HUMAN |
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