Anti-ATMIN Antibody (CAB7272)
- SKU:
- CAB7272
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-ATMIN Antibody |
抗体コード: | CAB7272 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-360 of human ATMIN (NP_056066.2). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | MCF7, Mouse testis, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-360 of human ATMIN (NP_056066.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | HAEK KHKC SKCS NSYG TEWD LKRH AEDC GKTF RCTC GCPY ASRT ALQS HIYR TGHE IPAE HRDP PSKK RKME NCAQ NQKL SNKT IESL NNQP IPRP DTQE LEAS EIKL EPSF EDSC GSNT DKQT LTTP PRYP QKLL LPKP KVAL VKLP VMQF SVMP VFVP TADS SAQP VVLG VDQG SATG AVHL MPLS VGTL ILGL DSEA C |
遺伝子ID: | 23300 |
Uniprot: | O43313 |
セルラーロケーション: | Nucleus |
計算された分子量: | 72kDa/88kDa |
観察された分子量: | 68-88kDa |
同義語: | ATMIN, ASCIZ, ZNF822 |
バックグラウンド: |
UniProt Protein Function: | ATMIN: Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM. Binds to the DYNLL1 promoter and activates its transcription. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA repair, damage; C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 16q23.2 Cellular Component: nucleus Molecular Function:dynein binding; protein binding; metal ion binding Biological Process: transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; response to DNA damage stimulus |
UniProt Code: | O43313 |
NCBI GenInfo Identifier: | 215273936 |
NCBI Gene ID: | 23300 |
NCBI Accession: | O43313.2 |
UniProt Secondary Accession: | O43313,Q68DC9, A8K4H8, |
UniProt Related Accession: | O43313 |
Molecular Weight: | 823 |
NCBI Full Name: | ATM interactor |
NCBI Synonym Full Names: | ATM interactor |
NCBI Official Symbol: | ATMIN |
NCBI Official Synonym Symbols: | ASCIZ; ZNF822 |
NCBI Protein Information: | ATM interactor; ATM INteracting protein; zinc finger protein 822; ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein; ATM/ATR-substrate CHK2-interacting zinc finger protein; ATM/ATR-substrate CHEK2-interacting zinc finger protein |
UniProt Protein Name: | ATM interactor |
UniProt Synonym Protein Names: | ATM/ATR-substrate CHK2-interacting zinc finger protein; ASCIZ; Zinc finger protein 822 |
Protein Family: | ATM interactor |
UniProt Gene Name: | ATMIN |
UniProt Entry Name: | ATMIN_HUMAN |
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