Anti-ATG3 Antibody (CAB19594)
- SKU:
- CAB19594
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Autophagy
Frequently bought together:
Description
抗体名: | Anti-ATG3 Antibody |
抗体コード: | CAB19594 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human Apg3 (Atg3). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Jurkat, U-87MG, K-562, Mouse brain, Mouse testis, Rat testis |
免疫原: | A synthesized peptide derived from human Apg3 (Atg3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 64422 |
Uniprot: | Q9NT62 |
セルラーロケーション: | |
計算された分子量: | 40kDa |
観察された分子量: | 40KDa |
同義語: | ATG3, APG3, APG3-LIKE, APG3L, PC3-96 |
バックグラウンド: | This gene encodes a ubiquitin-like-conjugating enzyme and is a component of ubiquitination-like systems involved in autophagy, the process of degradation, turnover and recycling of cytoplasmic constituents in eukaryotic cells. This protein is known to play a role in regulation of autophagy during cell death. A pseudogene of this gene is located on chromosome 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] |
UniProt Protein Function: | ATG3: an E2-like enzyme essential for Apg8p lipidation. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system; Enzyme, cellular metabolism; Autophagy; EC 6.3.2.- Chromosomal Location of Human Ortholog: 3q13.2 Cellular Component: cytoplasmic ubiquitin ligase complex; cytosol Molecular Function:APG12 conjugating enzyme activity; APG8 conjugating enzyme activity; enzyme binding; protein binding; small conjugating protein ligase activity Biological Process: autophagic vacuole formation; macroautophagy; mitochondrial fragmentation during apoptosis; mitochondrion degradation; protein modification process; protein targeting to membrane; protein ubiquitination |
NCBI Summary: | This gene encodes a ubiquitin-like-conjugating enzyme and is a component of ubiquitination-like systems involved in autophagy, the process of degradation, turnover and recycling of cytoplasmic constituents in eukaryotic cells. This protein is known to play a role in regulation of autophagy during cell death. A pseudogene of this gene is located on chromosome 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] |
UniProt Code: | Q9NT62 |
NCBI GenInfo Identifier: | 61212142 |
NCBI Gene ID: | 64422 |
NCBI Accession: | Q9NT62.1 |
UniProt Secondary Accession: | Q9NT62,Q6PKC5, Q9H6L9, |
UniProt Related Accession: | Q9NT62 |
Molecular Weight: | 35,467 Da |
NCBI Full Name: | Ubiquitin-like-conjugating enzyme ATG3 |
NCBI Synonym Full Names: | autophagy related 3 |
NCBI Official Symbol: | ATG3 |
NCBI Official Synonym Symbols: | APG3; APG3L; PC3-96; APG3-LIKE |
NCBI Protein Information: | ubiquitin-like-conjugating enzyme ATG3 |
UniProt Protein Name: | Ubiquitin-like-conjugating enzyme ATG3 |
UniProt Synonym Protein Names: | Autophagy-related protein 3; APG3-like; hApg3; Protein PC3-96 |
Protein Family: | Autophagy-related protein |
UniProt Gene Name: | ATG3 |
UniProt Entry Name: | ATG3_HUMAN |