Anti-ARR3 Antibody (CAB13009)
- SKU:
- CAB13009
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-ARR3 Antibody |
抗体コード: | CAB13009 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARR3 (NP_004303.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse eye, Rat eye |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARR3 (NP_004303.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MSKV FKKT SSNG KLSI YLGK RDFV DHVD TVEP IDGV VLVD PEYL KCRK LFVM LTCA FRYG RDDL EVIG LTFR KDLY VQTL QVVP AESS SPQG PLTV LQER LLHK LGDN AYPF TLQM VTNL PCSV TLQP GPED AGKP CGID FEVK SFCA ENPE ETVS KRDY VRLV VRKV QFAP PEAG PGPS AQTI RRFL LSAQ PLQL QAWM DREV HYHG EPIS VNVS INNC TNKV IKKI KISV DQIT DVVL YSLD KYTK TVFI QEFT ETVA |
遺伝子ID: | 407 |
Uniprot: | P36575 |
セルラーロケーション: | |
計算された分子量: | 39kDa/42kDa |
観察された分子量: | 42kDa |
同義語: | ARR3, ARRX, cArr |
バックグラウンド: | The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. |
UniProt Protein Function: | ARR3: May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins. Belongs to the arrestin family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: Xcen-q21 Cellular Component: cytoplasm; photoreceptor inner segment; photoreceptor outer segment; synapse Molecular Function:opsin binding; phosphoprotein binding; protein binding; protein domain specific binding Biological Process: endocytosis; regulation of protein amino acid phosphorylation; signal transduction; visual perception |
UniProt Code: | P36575 |
NCBI GenInfo Identifier: | 93189450 |
NCBI Gene ID: | 407 |
NCBI Accession: | P36575.2 |
UniProt Secondary Accession: | P36575,Q5JT23, Q5JT24, Q6IBF5, Q96EN2, B5B0B9, |
UniProt Related Accession: | P36575 |
Molecular Weight: | |
NCBI Full Name: | Arrestin-C |
NCBI Synonym Full Names: | arrestin 3 retinal (X-arrestin) |
NCBI Official Symbol: | ARR3 |
NCBI Official Synonym Symbols: | ARRX |
NCBI Protein Information: | arrestin-C |
UniProt Protein Name: | Arrestin-C |
UniProt Synonym Protein Names: | Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin |
Protein Family: | Arrestin |
UniProt Gene Name: | ARR3 |
UniProt Entry Name: | ARRC_HUMAN |
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