Anti-APPL Antibody (CAB8932)
- SKU:
- CAB8932
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
抗体名: | Anti-APPL Antibody |
抗体コード: | CAB8932 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human APPL |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | PC-12, BxPC-3, Mouse brain, Rat lung |
免疫原: | A synthesized peptide derived from human APPL |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 26060 |
Uniprot: | Q9UKG1 |
セルラーロケーション: | |
計算された分子量: | 85kDa |
観察された分子量: | 85KDa |
同義語: | APPL, DIP13alpha, MODY14 |
バックグラウンド: | The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008] |
UniProt Protein Function: | Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway. |
NCBI Summary: | The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UKG1 |
NCBI GenInfo Identifier: | 61213025 |
NCBI Gene ID: | 26060 |
NCBI Accession: | Q9UKG1.1 |
UniProt Secondary Accession: | Q9UKG1,Q9P2B9, |
UniProt Related Accession: | Q9UKG1 |
Molecular Weight: | 83 kDa |
NCBI Full Name: | DCC-interacting protein 13-alpha |
NCBI Synonym Full Names: | adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 |
NCBI Official Symbol: | APPL1 |
NCBI Official Synonym Symbols: | APPL; MODY14; DIP13alpha |
NCBI Protein Information: | DCC-interacting protein 13-alpha |
UniProt Protein Name: | DCC-interacting protein 13-alpha |
UniProt Synonym Protein Names: | Adapter protein containing PH domain, PTB domain and leucine zipper motif 1 |
Protein Family: | DCC-interacting protein |
UniProt Gene Name: | APPL1 |
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