Anti-APITD1 Antibody (CAB8293)
- SKU:
- CAB8293
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
抗体名: | APITD1 Rabbit Polyclonal Antibody |
抗体コード: | CAB8293 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human APITD1 (NP_954988.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | U-251MG, SW620, NCI-H460, MCF7, A-549 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human APITD1 (NP_954988.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MEEE AETE EQQR FSYQ QRLK AAVH YTVG CLCE EVAL DKEM QFSK QTIA AISE LTFR QCEN FAKD LEMF ARHA KRTT INTE DVKL LARR SNSL LKYI TDKS EEIA QINL ERKA QKKK KSED GSKN SRQP AEAG VVES EN |
遺伝子ID: | 378708 |
Uniprot: | Q8N2Z9 |
セルラーロケーション: | Chromosome, Nucleus, centromere, kinetochore |
計算された分子量: | 9kDa/15kDa/19kDa |
観察された分子量: | 16kDa |
同義語: | CENPS, APITD1, CENP-S, FAAP16, MHF1 |
バックグラウンド: | This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7. |
UniProt Code: | Q8N2Z9 |
NCBI GenInfo Identifier: | 395394019 |
NCBI Gene ID: | 100526739 |
NCBI Accession: | NP_001257446.1 |
UniProt Secondary Accession: | Q8N2Z9,Q8NFE5, Q8NFG5, |
Molecular Weight: | 15,893 Da |
NCBI Full Name: | APITD1-CORT protein isoform 4 |
NCBI Synonym Full Names: | APITD1-CORT readthrough |
NCBI Official Symbol: | APITD1-CORT |
NCBI Protein Information: | APITD1-CORT protein |
UniProt Protein Name: | Centromere protein S |
UniProt Synonym Protein Names: | Apoptosis-inducing TAF9-like domain-containing protein 1; FANCM-interacting histone fold protein 1; Fanconi anemia-associated polypeptide of 16 kDa |
Protein Family: | Centromere protein |
UniProt Gene Name: | APITD1 |
UniProt Entry Name: | CENPS_HUMAN |
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