Anti-AHCYL1 Antibody (CAB7773)
- SKU:
- CAB7773
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-AHCYL1 Antibody |
抗体コード: | CAB7773 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-260 of human AHCYL1 (NP_006612.2). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | 293T, U-251MG, SKOV3, Mouse brain, Rat spinal cord |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-260 of human AHCYL1 (NP_006612.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MATV TKAP KKQI QFAD DMQE FTKF PTKT GRRS LSRS ISQS STDS YSSA ASYT DSSD DEVS PREK QQTN SKGS SNFC VKNI KQAE FGRR EIEI AEQD MSAL ISLR KRAQ GEKP LAGA KIVG CTHI TAQT AVLI ETLC ALGA QCRW SACN IYST QNEV AAAL AEAG VAVF AWKG ESED DFWW CIDR CVNM DGWQ ANMI LDDG GDLT HWVY KKYP NVFK KIRG IVEE SVTG VH |
遺伝子ID: | 10768 |
Uniprot: | O43865 |
セルラーロケーション: | Apical cell membrane, Cytoplasm, Endoplasmic reticulum, Microsome, cytosol |
計算された分子量: | 53kDa/58kDa |
観察された分子量: | 59kDa |
同義語: | AHCYL1, DCAL, IRBIT, PPP1R78, PRO0233, XPVKONA |
バックグラウンド: | The protein encoded by this gene interacts with inositol 1, 4, 5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene. |
NCBI Summary: | This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011] |
UniProt Code: | O43865 |
NCBI GenInfo Identifier: | 109731743 |
NCBI Gene ID: | 9628 |
NCBI Accession: | BC113572 |
UniProt Secondary Accession: | O43865,O75576, O75577, Q7Z4K3, Q7Z4K4, Q7Z4K5, Q7Z4K6 Q8TE13, Q8TE14, Q8TE15, C9JE95, F8W7W5, |
UniProt Related Accession: | P49758 |
Molecular Weight: | 53,319 Da |
NCBI Full Name: | Homo sapiens regulator of G-protein signaling 6, mRNA |
NCBI Synonym Full Names: | regulator of G-protein signaling 6 |
NCBI Official Symbol: | RGS6 |
NCBI Official Synonym Symbols: | GAP; S914; HA117 |
NCBI Protein Information: | regulator of G-protein signaling 6 |
UniProt Protein Name: | Putative adenosylhomocysteinase 2 |
UniProt Synonym Protein Names: | DC-expressed AHCY-like molecule; IP(3)Rs binding protein released with IP(3); IRBIT; S-adenosyl-L-homocysteine hydrolase 2; S-adenosylhomocysteine hydrolase-like protein 1 |
Protein Family: | Regulator of G-protein signaling |
UniProt Gene Name: | AHCYL1 |
UniProt Entry Name: | SAHH2_HUMAN |
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