Anti-ADIPOR2 Antibody (CAB12777)
- SKU:
- CAB12777
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-ADIPOR2 Antibody |
抗体コード: | CAB12777 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human ADIPOR2 (NP_078827.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HT-29, HeLa, Mouse liver, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human ADIPOR2 (NP_078827.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MNEP TENR LGCS RTPE PDIR LRKG HQLD GTRR GDND SHQG DLEP ILEA SVLS SHHK KSSE EHEY SDEA PQED EGFM GMSP |
遺伝子ID: | 79602 |
Uniprot: | Q86V24 |
セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
計算された分子量: | 43kDa |
観察された分子量: | 44kDa |
同義語: | ADIPOR2, ACDCR2, PAQR2 |
バックグラウンド: |
UniProt Protein Function: | ADIPOR2: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin. Belongs to the ADIPOR family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Receptor, misc. Chromosomal Location of Human Ortholog: 12p13.31 Cellular Component: integral to membrane; plasma membrane Molecular Function:adiponectin binding; identical protein binding; hormone binding; protein heterodimerization activity; receptor activity Biological Process: positive regulation of glucose import; hormone-mediated signaling; heart development; adiponectin-mediated signaling pathway; fatty acid oxidation; female pregnancy; negative regulation of cell growth; response to nutrient |
NCBI Summary: | The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q86V24 |
NCBI GenInfo Identifier: | 38372190 |
NCBI Gene ID: | 79602 |
NCBI Accession: | Q86V24.1 |
UniProt Related Accession: | Q86V24 |
Molecular Weight: | 43kDa |
NCBI Full Name: | Adiponectin receptor protein 2 |
NCBI Synonym Full Names: | adiponectin receptor 2 |
NCBI Official Symbol: | ADIPOR2 |
NCBI Official Synonym Symbols: | PAQR2; ACDCR2 |
NCBI Protein Information: | adiponectin receptor protein 2 |
UniProt Protein Name: | Adiponectin receptor protein 2 |
UniProt Synonym Protein Names: | Progestin and adipoQ receptor family member II |
Protein Family: | Adiponectin receptor protein |
UniProt Gene Name: | ADIPOR2 |
UniProt Entry Name: | ADR2_HUMAN |
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