Anti-ADCY2 Antibody (CAB9805)
- SKU:
- CAB9805
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Description
抗体名: | Anti-ADCY2 Antibody |
抗体コード: | CAB9805 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 430-600 of human ADCY2 (NP_065433.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | SH-SY5Y, Rat eye |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 430-600 of human ADCY2 (NP_065433.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | VTLE HLNG AYKV EEGD GDIR DPYL KQHL VKTY FVIN PKGE RRSP QHLF RPRH TLDG AKMR ASVR MTRY LESW GAAK PFAH LHHR DSMT TENG KIST TDVP MGQH NFQN RTLR TKSQ KKRF EEEL NERM IQAI DGIN AQKQ WLKS EDIQ RISL LFYN KVLE KEYR ATAL PAF |
遺伝子ID: | 108 |
Uniprot: | Q08462 |
セルラーロケーション: | Cell membrane, Cytoplasm, Membrane, Multi-pass membrane protein |
計算された分子量: | 103kDa/123kDa |
観察された分子量: | 150kDa |
同義語: | ADCY2, AC2, HBAC2 |
バックグラウンド: | This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex. |
UniProt Protein Function: | ADCY2: This is a membrane-bound, calmodulin-insensitive adenylyl cyclase. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Adenylyl cyclase; Transporter, aquaporin family; Nucleotide Metabolism - purine; Membrane protein, multi-pass; EC 4.6.1.1; Transporter; Lyase Chromosomal Location of Human Ortholog: 5p15.3 Cellular Component: cytoplasm; dendrite; integral to plasma membrane; intracellular; lipid raft; membrane; plasma membrane Molecular Function:adenylate cyclase activity; adenylate cyclase binding; magnesium ion binding; manganese ion binding; protein heterodimerization activity Biological Process: activation of protein kinase A; adenylate cyclase activation; cAMP biosynthetic process; cAMP-mediated signaling; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; renal water homeostasis |
NCBI Summary: | This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q08462 |
NCBI GenInfo Identifier: | 118572617 |
NCBI Gene ID: | 108 |
NCBI Accession: | Q08462.5 |
UniProt Secondary Accession: | Q08462,Q2NKL8, Q9UDB2, Q9UPU2, B7Z2C1, |
UniProt Related Accession: | Q08462 |
Molecular Weight: | 103,158 Da |
NCBI Full Name: | Adenylate cyclase type 2 |
NCBI Synonym Full Names: | adenylate cyclase 2 |
NCBI Official Symbol: | ADCY2 |
NCBI Official Synonym Symbols: | AC2; HBAC2 |
NCBI Protein Information: | adenylate cyclase type 2 |
UniProt Protein Name: | Adenylate cyclase type 2 |
UniProt Synonym Protein Names: | ATP pyrophosphate-lyase 2; Adenylate cyclase type II; Adenylyl cyclase 2 |
Protein Family: | Adenylate cyclase |
UniProt Gene Name: | ADCY2 |
UniProt Entry Name: | ADCY2_HUMAN |