Anti-ADAMTS9 Antibody (CAB17928)
- SKU:
- CAB17928
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-ADAMTS9 Antibody |
抗体コード: | CAB17928 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant protein of human ADAMTS9. |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: |
免疫原: | Recombinant protein of human ADAMTS9. |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 56999 |
Uniprot: | Q9P2N4 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | Refer to figures |
同義語: | ADAMTS9 |
バックグラウンド: | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. Members of the ADAMTS family have been implicated in the cleavage of proteoglycans, the control of organ shape during development, and the inhibition of angiogenesis. This gene is localized to chromosome 3p14.3-p14.2, an area known to be lost in hereditary renal tumors. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. |
UniProt Protein Function: | Cleaves the large aggregating proteoglycans, aggrecan (at the '1838-Glu-|-Ala-1839' site) and versican (at the '1428-Glu-|-Ala-1429' site). Has a protease-independent function in promoting the transport from the endoplasmic reticulum to the Golgi apparatus of a variety of secretory cargos. |
NCBI Summary: | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. Members of the ADAMTS family have been implicated in the cleavage of proteoglycans, the control of organ shape during development, and the inhibition of angiogenesis. This gene is localized to chromosome 3p14.3-p14.2, an area known to be lost in hereditary renal tumors. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016] |
UniProt Code: | Q9P2N4 |
NCBI GenInfo Identifier: | 974005284 |
NCBI Gene ID: | 56999 |
NCBI Accession: | NP_001305710.1 |
UniProt Secondary Accession: | Q9P2N4,Q9NR29, A1L4L0, B7ZVX9, B9ZVN0, |
UniProt Related Accession: | Q9P2N4 |
Molecular Weight: | 212 |
NCBI Full Name: | A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform 4 |
NCBI Synonym Full Names: | ADAM metallopeptidase with thrombospondin type 1 motif 9 |
NCBI Official Symbol: | ADAMTS9 |
NCBI Protein Information: | A disintegrin and metalloproteinase with thrombospondin motifs 9 |
UniProt Protein Name: | A disintegrin and metalloproteinase with thrombospondin motifs 9 |
UniProt Gene Name: | ADAMTS9 |