Anti-ACSM2A Antibody (CAB15563)
- SKU:
- CAB15563
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-ACSM2A Antibody |
抗体コード: | CAB15563 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 418-577 of human ACSM2A (NP_001295101.1). |
申し込み: | WB |
推奨希釈: | WB 1:200 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse kidney, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 418-577 of human ACSM2A (NP_001295101.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | RPIG IFSG YVDN PDKT AANI RGDF WLLG DRGI KDED GYFQ FMGR ANDI INSS GYRI GPSE VENA LMEH PAVV ETAV ISSP DPVR GEVV KAFV VLAS QFLS HDPE QLTK ELQQ HVKS VTAP YKYP RKIE FVLN LPKT VTGK IQRA KLRD KEWK MSGK ARAQ |
遺伝子ID: | 123876 |
Uniprot: | Q08AH3 |
セルラーロケーション: | Mitochondrion matrix |
計算された分子量: | 64kDa |
観察された分子量: | 64kDa |
同義語: | ACSM2A, A-923A4.1, ACSM2 |
バックグラウンド: | This gene encodes a mitochondrial acyl-coenzyme A synthetase that is specific for medium chain fatty acids. These enzymes catalyze fatty acid activation, the first step of fatty acid metabolism, through the transfer of acyl-CoA. These enzymes also participate in the glycine conjugation pathway in the detoxification of xenobiotics such as benzoate and ibuprofen. Expression levels of this gene in the kidney may be correlated with kidney function. This gene and its paralog ACSM2B (Gene ID: 348158), both present on chromosome 16, likely arose from a chromosomal duplication event. |
UniProt Protein Function: | ACSM2A: an acyl-CoA synthetase. Acyl-CoA synthetases catalyze the first reaction of amino acid conjugation in fatty acid metabolism and of many xenobiotic carboxylic acids. A liver enzyme implicated in the metabolism of xenobiotic carboxylic acids such as pesticides, arylpropionate anti-inflammatory drugs and hypolipidaemic clofibrate and its congeners. |
UniProt Protein Details: | Protein type:Mitochondrial; Ligase; EC 6.2.1.2; Carbohydrate Metabolism - butanoate Chromosomal Location of Human Ortholog: 16p12.3 Molecular Function:butyrate-CoA ligase activity |
UniProt Code: | Q08AH3 |
NCBI GenInfo Identifier: | 257050995 |
NCBI Gene ID: | 123876 |
NCBI Accession: | Q08AH3.2 |
UniProt Secondary Accession: | Q08AH3,O75202, B3KTT9, |
UniProt Related Accession: | Q08AH3 |
Molecular Weight: | 64,223 Da |
NCBI Full Name: | Acyl-coenzyme A synthetase ACSM2A, mitochondrial |
NCBI Synonym Full Names: | acyl-CoA synthetase medium-chain family member 2A |
NCBI Official Symbol: | ACSM2A |
NCBI Official Synonym Symbols: | ACSM2; A-923A4.1 |
NCBI Protein Information: | acyl-coenzyme A synthetase ACSM2A, mitochondrial |
UniProt Protein Name: | Acyl-coenzyme A synthetase ACSM2A, mitochondrial |
UniProt Synonym Protein Names: | Acyl-CoA synthetase medium-chain family member 2A; Butyrate--CoA ligase 2A; Butyryl-coenzyme A synthetase 2A; Middle-chain acyl-CoA synthetase 2A |
Protein Family: | Acyl-coenzyme A synthetase |
UniProt Gene Name: | ACSM2A |
UniProt Entry Name: | ACS2A_HUMAN |
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