Anti-ACOX2 Antibody (CAB12796)
- SKU:
- CAB12796
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-ACOX2 Antibody |
抗体コード: | CAB12796 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human ACOX2 (NP_003491.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | U-87MG, HT-29, Mouse liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human ACOX2 (NP_003491.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MGSP VHRV SLGD TWSR QMHP DIES ERYM QSFD VERL TNIL DGGA QNTA LRRK VESI IHSY PEFS CKDN YFMT QNER YKAA MRRA FHIR LIAR RLGW LEDG RELG YAYR ALSG DVAL NIHR VFVR ALRS LGSE EQIA KWDP LCKN IQII AT |
遺伝子ID: | 8309 |
Uniprot: | Q99424 |
セルラーロケーション: | Peroxisome |
計算された分子量: | 76kDa |
観察された分子量: | 77kDa |
同義語: | ACOX2, BCOX, BRCACOX, BRCOX, CBAS6, THCCox |
バックグラウンド: | The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children. |
UniProt Protein Function: | ACOX2: Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids. Belongs to the acyl-CoA oxidase family. |
UniProt Protein Details: | Protein type:EC 1.17.99.3; Lipid Metabolism - primary bile acid biosynthesis; Oxidoreductase Chromosomal Location of Human Ortholog: 3p14.3 Cellular Component: intracellular membrane-bound organelle; mitochondrion; peroxisomal matrix; peroxisome Molecular Function:acyl-CoA binding; acyl-CoA dehydrogenase activity; acyl-CoA oxidase activity; electron carrier activity; FAD binding; pristanoyl-CoA oxidase activity; receptor binding Biological Process: bile acid biosynthetic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty acid beta-oxidation using acyl-CoA oxidase; lipid homeostasis |
NCBI Summary: | The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children. [provided by RefSeq, Mar 2009] |
UniProt Code: | Q99424 |
NCBI GenInfo Identifier: | 17366636 |
NCBI Gene ID: | 8309 |
NCBI Accession: | Q99424.1 |
UniProt Secondary Accession: | Q99424,A6NF16, B2R8U5, |
UniProt Related Accession: | Q99424 |
Molecular Weight: | 76,827 Da |
NCBI Full Name: | Peroxisomal acyl-coenzyme A oxidase 2 |
NCBI Synonym Full Names: | acyl-CoA oxidase 2 |
NCBI Official Symbol: | ACOX2 |
NCBI Official Synonym Symbols: | BCOX; BRCOX; THCCox; BRCACOX |
NCBI Protein Information: | peroxisomal acyl-coenzyme A oxidase 2 |
UniProt Protein Name: | Peroxisomal acyl-coenzyme A oxidase 2 |
UniProt Synonym Protein Names: | 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; Trihydroxycoprostanoyl-CoA oxidase; THCA-CoA oxidase; THCCox |
Protein Family: | Peroxisomal acyl-coenzyme A oxidase |
UniProt Gene Name: | ACOX2 |
UniProt Entry Name: | ACOX2_HUMAN |
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