ADRA1A Antibody (PACO19094)
- SKU:
- PACO19094
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ADRA1A Antibody (PACO19094) |
抗体コード: | PACO19094 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human ADRA1A |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19094(ADRA1A Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: PC3 cells, Raji cells, Primary antibody: PACO19094(ADRA1A Antibody) at dilution 1/337.5, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19094(ADRA1A Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. |
シノニム: | adrenoceptor α 1A |
UniProt Protein Function: | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes. |
NCBI Summary: | Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008] |
UniProt Code: | P35348 |
NCBI GenInfo Identifier: | 1168246 |
NCBI Gene ID: | 148 |
NCBI Accession: | P35348.2 |
UniProt Secondary Accession: | P35348,O60451, Q13675, Q13729, A8K0I3, B0ZBD1, B0ZBD2 B0ZBD4, B0ZBD5, B0ZBD6, B0ZBD8, B0ZBD9, |
UniProt Related Accession: | P35348 |
Molecular Weight: | 40,638 Da |
NCBI Full Name: | Alpha-1A adrenergic receptor |
NCBI Synonym Full Names: | adrenoceptor alpha 1A |
NCBI Official Symbol: | ADRA1A |
NCBI Official Synonym Symbols: | ADRA1C; ADRA1L1; ALPHA1AAR |
NCBI Protein Information: | alpha-1A adrenergic receptor |
UniProt Protein Name: | Alpha-1A adrenergic receptor |
UniProt Synonym Protein Names: | Alpha-1A adrenoreceptor; Alpha-1A adrenoceptor; Alpha-1C adrenergic receptor; Alpha-adrenergic receptor 1c |
Protein Family: | Alpha-1A adrenergic receptor |
UniProt Gene Name: | ADRA1A |
UniProt Entry Name: | ADA1A_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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