ADCY1 Antibody, FITC conjugated (PACO46476)
- SKU:
- PACO46476
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Description
抗体名: | ADCY1 Antibody, FITC conjugated (PACO46476) |
抗体コード: | PACO46476 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Adenylate cyclase type 1 protein (416-610AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels (By similarity). May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (By similarity). |
シノニム: | Adenylate cyclase type 1 (EC 4.6.1.1) (ATP pyrophosphate-lyase 1) (Adenylate cyclase type I) (Adenylyl cyclase 1) (Ca(2+)/calmodulin-activated adenylyl cyclase), ADCY1 |
UniProt Protein Function: | ADCY1: a calmodulin-sensitive adenylyl cyclase expressed in brain. The mouse protein is involved in pattern formation of the brain. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Transporter; Nucleotide Metabolism - purine; EC 4.6.1.1; Membrane protein, multi-pass; Lyase; Transporter, aquaporin family; Adenylyl cyclase Chromosomal Location of Human Ortholog: 7p12.3 Cellular Component: cytoplasm; integral to plasma membrane; lipid raft; nucleus; plasma membrane Molecular Function:adenylate cyclase activity; ATP binding; calcium- and calmodulin-responsive adenylate cyclase activity; calmodulin binding; metal ion binding Biological Process: activation of protein kinase A; axonogenesis; cAMP biosynthetic process; cAMP-mediated signaling; circadian rhythm; energy reserve metabolic process; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; innate immune response; long-term memory; nerve growth factor receptor signaling pathway; phospholipase C activation; regulation of circadian rhythm; renal water homeostasis; response to drug; response to lithium ion; signal transduction; synaptic transmission; transmembrane transport; water transport Disease: Deafness, Autosomal Recessive 44 |
NCBI Summary: | This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q08828 |
NCBI GenInfo Identifier: | 62512172 |
NCBI Gene ID: | 107 |
NCBI Accession: | Q08828.2 |
UniProt Secondary Accession: | Q08828,Q75MI1, A4D2L8, |
UniProt Related Accession: | Q08828 |
Molecular Weight: | 123,440 Da |
NCBI Full Name: | Adenylate cyclase type 1 |
NCBI Synonym Full Names: | adenylate cyclase 1 (brain) |
NCBI Official Symbol: | ADCY1 |
NCBI Official Synonym Symbols: | AC1; DFNB44 |
NCBI Protein Information: | adenylate cyclase type 1 |
UniProt Protein Name: | Adenylate cyclase type 1 |
UniProt Synonym Protein Names: | ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca(2+)/calmodulin-activated adenylyl cyclase |
Protein Family: | Adenylate cyclase |
UniProt Gene Name: | ADCY1 |
UniProt Entry Name: | ADCY1_HUMAN |