ZMAT3 Antibody (PACO16825)
- SKU:
- PACO16825
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ZMAT3 Antibody (PACO16825) |
抗体コード: | PACO16825 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human ZMAT3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO16825(ZMAT3 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO16825(ZMAT3 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid, |
シノニム: | zinc finger, matrin-type 3 |
UniProt Protein Function: | ZMAT3: Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 3q26.32 Cellular Component: nucleolus Molecular Function:protein binding; zinc ion binding Biological Process: protein transport; apoptosis; positive regulation of apoptosis; regulation of growth; response to DNA damage stimulus |
NCBI Summary: | This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9HA38 |
NCBI GenInfo Identifier: | 74734128 |
NCBI Gene ID: | 64393 |
NCBI Accession: | Q9HA38.1 |
UniProt Secondary Accession: | Q9HA38,Q96A21, B3KVA6, D3DNR1, |
UniProt Related Accession: | Q9HA38 |
Molecular Weight: | 289 |
NCBI Full Name: | Zinc finger matrin-type protein 3 |
NCBI Synonym Full Names: | zinc finger, matrin-type 3 |
NCBI Official Symbol: | ZMAT3 |
NCBI Official Synonym Symbols: | WIG1; WIG-1; PAG608 |
NCBI Protein Information: | zinc finger matrin-type protein 3; ZMAT3; WIG-1/PAG608 protein; zinc finger protein WIG1; zinc finger protein WIG-1; zinc finger, matrin type 3; p53 target zinc finger protein; p53-activated gene 608 protein |
UniProt Protein Name: | Zinc finger matrin-type protein 3 |
UniProt Synonym Protein Names: | Zinc finger protein WIG-1; p53-activated gene 608 protein |
Protein Family: | Zinc finger matrin-type protein |
UniProt Gene Name: | ZMAT3 |
UniProt Entry Name: | ZMAT3_HUMAN |
Antibodies | ELISA Kits |
Anti-ZMAT3 Antibody (CAB4928) | Human PAG608 / ZMAT3 ELISA Kit |
Human Zinc finger matrin-type protein 3 (ZMAT3) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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