WDR5 Antibody (PACO17450)
- SKU:
- PACO17450
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | WDR5 Antibody (PACO17450) |
抗体コード: | PACO17450 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human WDR5 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17450(WDR5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-6: A375, 231 and PC3 cell, human lung cancer tissue, hela and NIH/3T3 cell, Primary antibody: PACO17450(WDR5 Antibody) at dilution 1/300 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17450(WDR5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acid, typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. |
シノニム: | WD repeat domain 5 |
UniProt Protein Function: | WDR5: a WD40 repeat protein. May accelerate osteoblast differentiation. Interacts with HCFC1. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 9q34 Cellular Component: histone acetyltransferase complex; histone methyltransferase complex; nucleoplasm; nucleus Molecular Function:histone acetyltransferase activity (H4-K16 specific); histone lysine N-methyltransferase activity (H3-K4 specific); histone-lysine N-methyltransferase activity; methylated histone residue binding; protein binding Biological Process: histone H3-K4 methylation |
NCBI Summary: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
UniProt Code: | P61964 |
NCBI GenInfo Identifier: | 48429182 |
NCBI Gene ID: | 11091 |
NCBI Accession: | P61964.1 |
UniProt Secondary Accession: | P61964,Q91VA5, Q9NWX7, Q9UGP9, |
UniProt Related Accession: | P61964 |
Molecular Weight: | 36,588 Da |
NCBI Full Name: | WD repeat-containing protein 5 |
NCBI Synonym Full Names: | WD repeat domain 5 |
NCBI Official Symbol: | WDR5 |
NCBI Official Synonym Symbols: | SWD3; BIG-3; CFAP89 |
NCBI Protein Information: | WD repeat-containing protein 5 |
UniProt Protein Name: | WD repeat-containing protein 5 |
UniProt Synonym Protein Names: | BMP2-induced 3-kb gene protein |
Protein Family: | WD repeat-containing protein |
UniProt Gene Name: | WDR5 |
UniProt Entry Name: | WDR5_HUMAN |