VASH1 Antibody, HRP conjugated (PACO36803)
- SKU:
- PACO36803
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | VASH1 Antibody, HRP conjugated (PACO36803) |
抗体コード: | PACO36803 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Vasohibin-1 protein (1-204AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity. |
シノニム: | Vasohibin-1, VASH1, KIAA1036 VASH |
UniProt Protein Function: | VASH1: Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity. Belongs to the vasohibin family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 14q24.3 Cellular Component: extracellular space; apical part of cell; endoplasmic reticulum; cytoplasm Biological Process: negative regulation of angiogenesis; negative regulation of endothelial cell proliferation; response to wounding; angiogenesis; cell cycle arrest; negative regulation of blood vessel endothelial cell migration |
UniProt Code: | Q7L8A9 |
NCBI GenInfo Identifier: | 62511163 |
NCBI Gene ID: | 22846 |
NCBI Accession: | Q7L8A9.1 |
UniProt Secondary Accession: | Q7L8A9,Q96H02, Q9UBF4, Q9Y629, |
UniProt Related Accession: | Q7L8A9 |
Molecular Weight: | 365 |
NCBI Full Name: | Vasohibin-1 |
NCBI Synonym Full Names: | vasohibin 1 |
NCBI Official Symbol: | VASH1 |
NCBI Official Synonym Symbols: | KIAA1036 |
NCBI Protein Information: | vasohibin-1 |
UniProt Protein Name: | Vasohibin-1 |
Protein Family: | Vasohibin |
UniProt Gene Name: | VASH1 |
UniProt Entry Name: | VASH1_HUMAN |