UGT8 Antibody, HRP conjugated (PACO50531)
- SKU:
- PACO50531
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | UGT8 Antibody, HRP conjugated (PACO50531) |
抗体コード: | PACO50531 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human 2-hydroxyacylsphingosine 1-beta-galactosyltransferase protein (38-402AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. |
シノニム: | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (EC 2.4.1.47) (Ceramide UDP-galactosyltransferase) (Cerebroside synthase) (UDP-galactose-ceramide galactosyltransferase), UGT8, CGT UGT4 |
UniProt Protein Function: | UGT8: Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Belongs to the UDP-glycosyltransferase family. |
UniProt Protein Details: | Protein type:Transferase; Lipid Metabolism - sphingolipid; EC 2.4.1.45; Membrane protein, integral Chromosomal Location of Human Ortholog: 4q26 Cellular Component: intracellular membrane-bound organelle; integral to membrane Molecular Function:UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity; glucuronosyltransferase activity; 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity Biological Process: central nervous system development; flavonoid biosynthetic process; galactosylceramide biosynthetic process; axon cargo transport; cytoskeleton organization and biogenesis; neurite morphogenesis; cellular response to hormone stimulus; peripheral nervous system development; paranodal junction assembly |
NCBI Summary: | The protein encoded by this gene belongs to the UDP-glycosyltransferase family. It catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central and peripheral nervous systems. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011] |
UniProt Code: | Q16880 |
NCBI GenInfo Identifier: | 189491660 |
NCBI Gene ID: | 7368 |
NCBI Accession: | NP_001121646.1 |
UniProt Secondary Accession: | Q16880,O00196, B3KXU7, |
UniProt Related Accession: | Q16880 |
Molecular Weight: | 61,438 Da |
NCBI Full Name: | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase |
NCBI Synonym Full Names: | UDP glycosyltransferase 8 |
NCBI Official Symbol: | UGT8 |
NCBI Official Synonym Symbols: | CGT; UGT4 |
NCBI Protein Information: | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; UDP-galactose ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase; ceramide UDP-galactosyltransferase; cerebroside synthase; uridine diphosphate glycosyltransferase 8 |
UniProt Protein Name: | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase |
UniProt Synonym Protein Names: | Ceramide UDP-galactosyltransferase; Cerebroside synthase; UDP-galactose-ceramide galactosyltransferase |
Protein Family: | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase |
UniProt Gene Name: | UGT8 |
UniProt Entry Name: | CGT_HUMAN |