TRPC1 Antibody (PACO12937)
- SKU:
- PACO12937
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TRPC1 Antibody (PACO12937) |
抗体コード: | PACO12937 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human TRPC1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | transient receptor potential cation channel, subfamily C, member 1;TRPC1;HTRP-1;MGC133334;MGC133335;TRP1 ; |
UniProt Protein Function: | TRPC1: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Channel, calcium; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 3q23 Cellular Component: integral to plasma membrane; plasma membrane; receptor complex Molecular Function:calcium channel activity; cation channel activity; protein binding; store-operated calcium channel activity Biological Process: calcium ion transport; cytosolic calcium ion homeostasis; manganese ion transport; melanin biosynthetic process; positive regulation of release of sequestered calcium ion into cytosol; response to calcium ion |
NCBI Summary: | The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
UniProt Code: | P48995 |
NCBI GenInfo Identifier: | 1351302 |
NCBI Gene ID: | 7220 |
NCBI Accession: | P48995.1 |
UniProt Secondary Accession: | P48995,Q14CE4, |
UniProt Related Accession: | P48995 |
Molecular Weight: | 87,617 Da |
NCBI Full Name: | Short transient receptor potential channel 1 |
NCBI Synonym Full Names: | transient receptor potential cation channel subfamily C member 1 |
NCBI Official Symbol: | TRPC1 |
NCBI Official Synonym Symbols: | TRP1; HTRP-1 |
NCBI Protein Information: | short transient receptor potential channel 1 |
UniProt Protein Name: | Short transient receptor potential channel 1 |
UniProt Synonym Protein Names: | Transient receptor protein 1; TRP-1 |
Protein Family: | Indole-3-glycerol phosphate synthase |
UniProt Gene Name: | TRPC1 |