TRAF5 Antibody (PACO30774)
- SKU:
- PACO30774
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | TRAF5 Antibody (PACO30774) |
抗体コード: | PACO30774 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human TNF receptor-associated factor 5 protein (1-557AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human spleen tissue using PACO30774 at dilution of 1:100. |
バックグラウンド: | Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR. |
シノニム: | TNF receptor-associated factor 5 (RING finger protein 84), TRAF5, RNF84 |
UniProt Protein Function: | TRAF5: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Belongs to the TNF receptor-associated factor family. A subfamily. |
UniProt Protein Details: | Protein type:Adaptor/scaffold; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 1q32 Cellular Component: centrosome; internal side of plasma membrane; cytoplasm; cytosol Molecular Function:protein binding; signal transducer activity; zinc ion binding; thioesterase binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity Biological Process: regulation of apoptosis; positive regulation of I-kappaB kinase/NF-kappaB cascade; apoptosis; positive regulation of cell proliferation; protein ubiquitination; positive regulation of transcription factor activity; signal transduction; activation of NF-kappaB transcription factor |
NCBI Summary: | The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] |
UniProt Code: | O00463 |
NCBI GenInfo Identifier: | 30580600 |
NCBI Gene ID: | 7188 |
NCBI Accession: | O00463.2 |
UniProt Related Accession: | O00463 |
Molecular Weight: | Observed: 55 kDaPredicted: 65 kDa |
NCBI Full Name: | TNF receptor-associated factor 5 |
NCBI Synonym Full Names: | TNF receptor associated factor 5 |
NCBI Official Symbol: | TRAF5 |
NCBI Official Synonym Symbols: | RNF84; MGC:39780 |
NCBI Protein Information: | TNF receptor-associated factor 5 |
UniProt Protein Name: | TNF receptor-associated factor 5 |
UniProt Synonym Protein Names: | RING finger protein 84 |
Protein Family: | TNF receptor-associated factor |
UniProt Gene Name: | TRAF5 |
UniProt Entry Name: | TRAF5_HUMAN |
Antibodies | ELISA Kits |
Anti-TRAF5 Antibody (CAB2536) | Human TRAF5 (TNF receptor associated factors 5 )ELISA Kit (HUFI05988) |
TRAF5 Antibody (PACO12885) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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