TBX2 Antibody, FITC conjugated (PACO54472)
- SKU:
- PACO54472
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | TBX2 Antibody, FITC conjugated (PACO54472) |
抗体コード: | PACO54472 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human T-box transcription factor TBX2 protein (299-573AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Acts as a negative regulator of PML function in cellular senescence. May be required for cardiac atrioventricular canal formation. |
シノニム: | T-box transcription factor TBX2 (T-box protein 2), TBX2 |
UniProt Protein Function: | TBX2: Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary. |
UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 17q23.2 Cellular Component: nucleus Molecular Function:DNA binding; protein binding; sequence-specific DNA binding Biological Process: cardiac muscle development; cell aging; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic heart tube development; heart looping; muscle cell fate determination; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of cardiac muscle cell proliferation; positive regulation of cell proliferation; regulation of heart contraction |
NCBI Summary: | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q13207 |
NCBI GenInfo Identifier: | 294862490 |
NCBI Gene ID: | 6909 |
NCBI Accession: | Q13207.3 |
UniProt Secondary Accession: | Q13207,Q16424, Q7Z647, |
UniProt Related Accession: | Q13207 |
Molecular Weight: | 75,066 Da |
NCBI Full Name: | T-box transcription factor TBX2 |
NCBI Synonym Full Names: | T-box 2 |
NCBI Official Symbol: | TBX2 |
NCBI Protein Information: | T-box transcription factor TBX2 |
UniProt Protein Name: | T-box transcription factor TBX2 |
Protein Family: | T-box transcription factor |
UniProt Gene Name: | TBX2 |
UniProt Entry Name: | TBX2_HUMAN |