TAF6 Antibody, HRP conjugated (PACO46263)
- SKU:
- PACO46263
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | TAF6 Antibody, HRP conjugated (PACO46263) |
抗体コード: | PACO46263 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Transcription initiation factor TFIID subunit 6 protein (627-677AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. |
シノニム: | Transcription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80), TAF6, TAF2E TAFII70 |
UniProt Protein Function: | TAF6: TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Belongs to the TAF6 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription initiation complex Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: cytoplasm; nucleoplasm; nucleus; transcription factor TFIID complex Molecular Function:DNA binding; protein binding; transcription factor activity Biological Process: negative regulation of cell cycle; RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation; transcription initiation from RNA polymerase II promoter |
NCBI Summary: | Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010] |
UniProt Code: | P49848 |
NCBI GenInfo Identifier: | 1729810 |
NCBI Gene ID: | 6878 |
NCBI Accession: | P49848.1 |
UniProt Secondary Accession: | P49848,Q6AI29, A4D2B2, A4D2B3, B4DT11, D6W5U2, |
UniProt Related Accession: | P49848 |
Molecular Weight: | 76,995 Da |
NCBI Full Name: | Transcription initiation factor TFIID subunit 6 |
NCBI Synonym Full Names: | TATA-box binding protein associated factor 6 |
NCBI Official Symbol: | TAF6 |
NCBI Official Synonym Symbols: | TAF2E; TAFII70; TAFII80; TAFII85; MGC:8964; TAFII-70; TAFII-80; TAF(II)70; TAF(II)80 |
NCBI Protein Information: | transcription initiation factor TFIID subunit 6 |
UniProt Protein Name: | Transcription initiation factor TFIID subunit 6 |
UniProt Synonym Protein Names: | RNA polymerase II TBP-associated factor subunit E; Transcription initiation factor TFIID 70 kDa subunit; TAF(II)70; TAFII-70; TAFII70; Transcription initiation factor TFIID 80 kDa subunit; TAF(II)80; TAFII-80; TAFII80 |
Protein Family: | Transcription initiation factor |
UniProt Gene Name: | TAF6 |
UniProt Entry Name: | TAF6_HUMAN |