SYN1 Antibody (PACO19833)
- SKU:
- PACO19833
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SYN1 Antibody (PACO19833) |
抗体コード: | PACO19833 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Synthetic peptide of human SYN1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19833(SYN1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Mouse brain tissue, Primary antibody: PACO19833(SYN1 Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO19833(SYN1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. |
シノニム: | synapsin I |
UniProt Protein Function: | SYN1: neuronal phosphoprotein which associates with the cytoplasmic surface of synaptic vesicles and binds to the cytoskeleton. May function in the regulation of neurotransmitter release and of axonogenesis and synaptogenesis. Mutations may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Two differentially spiced isoforms have been reported. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: synaptic vesicle Molecular Function:ATP binding; protein binding; protein kinase binding; transporter activity Biological Process: regulation of neurotransmitter secretion; synaptic transmission Disease: Epilepsy, X-linked, With Variable Learning Disabilities And Behavior Disorders |
NCBI Summary: | This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
UniProt Code: | P17600 |
NCBI GenInfo Identifier: | 73920800 |
NCBI Gene ID: | 6853 |
NCBI Accession: | P17600.3 |
UniProt Secondary Accession: | P17600,O75825, Q5H9A9, B1AJQ1, |
UniProt Related Accession: | P17600 |
Molecular Weight: | 70,033 Da |
NCBI Full Name: | Synapsin-1 |
NCBI Synonym Full Names: | synapsin I |
NCBI Official Symbol: | SYN1 |
NCBI Official Synonym Symbols: | SYNI; SYN1a; SYN1b |
NCBI Protein Information: | synapsin-1 |
UniProt Protein Name: | Synapsin-1 |
UniProt Synonym Protein Names: | Brain protein 4.1; Synapsin I |
Protein Family: | Synapsin |
UniProt Gene Name: | SYN1 |
UniProt Entry Name: | SYN1_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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