SV2A Antibody (PACO18945)
- SKU:
- PACO18945
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SV2A Antibody (PACO18945) |
抗体コード: | PACO18945 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human SV2A |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18945(SV2A Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18945(SV2A Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This protein plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.It is identified as the brain binding-site for the antiepileptic drug levetiracetam/lev. |
シノニム: | synaptic vesicle glycoprotein 2A |
UniProt Protein Function: | SV2A: Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles. Belongs to the major facilitator superfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Vesicle Chromosomal Location of Human Ortholog: 1q21.2 Cellular Component: synaptic vesicle; neuron projection; synaptic vesicle membrane; endoplasmic reticulum; cytoplasm; plasma membrane; presynaptic active zone; integral to membrane; intercellular junction; neuromuscular junction Molecular Function:receptor activity; transmembrane transporter activity; protein kinase binding Biological Process: cellular calcium ion homeostasis; neurotransmitter transport; pathogenesis; transmembrane transport |
UniProt Code: | Q7L0J3 |
NCBI GenInfo Identifier: | 523498712 |
NCBI Gene ID: | 9900 |
NCBI Accession: | NP_001265648.1 |
UniProt Secondary Accession: | Q7L0J3,O94841, Q5QNX8, Q7Z3L6, Q8NBJ6, Q9BVZ9, D3DUZ7 |
UniProt Related Accession: | Q7L0J3 |
Molecular Weight: | 82,695 Da |
NCBI Full Name: | synaptic vesicle glycoprotein 2A isoform 2 |
NCBI Synonym Full Names: | synaptic vesicle glycoprotein 2A |
NCBI Official Symbol: | SV2A |
NCBI Official Synonym Symbols: | SV2 |
NCBI Protein Information: | synaptic vesicle glycoprotein 2A |
UniProt Protein Name: | Synaptic vesicle glycoprotein 2A |
Protein Family: | Synaptic vesicle glycoprotein |
UniProt Gene Name: | SV2A |
UniProt Entry Name: | SV2A_HUMAN |
Antibodies |
Anti-SV2A Antibody (CAB17868) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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