SULF2 Antibody (PACO50762)
- SKU:
- PACO50762
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SULF2 Antibody (PACO50762) |
抗体コード: | PACO50762 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Recombinant Human Extracellular sulfatase Sulf-2 protein (463-660AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Hela whole cell lysate, Mouse brain tissue, Rat lung tissue. All lanes: SULF2 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 101 kDa. Observed band size: 140 kDa.. | |
Immunohistochemistry of paraffin-embedded human heart tissue using PACO50762 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human salivary gland tissue using PACO50762 at dilution of 1:100. |
バックグラウンド: | Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. |
シノニム: | Extracellular sulfatase Sulf-2 (hSulf-2) (EC 3.1.6), SULF2, KIAA1247 |
UniProt Protein Function: | SULF2: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; EC 3.1.6.-; Hydrolase; Secreted Chromosomal Location of Human Ortholog: 20q13.12 Cellular Component: cell surface; endoplasmic reticulum; plasma membrane Molecular Function:arylsulfatase activity; N-acetylglucosamine-6-sulfatase activity Biological Process: cartilage development; chondrocyte development; embryonic skeletal development; esophagus smooth muscle contraction; glomerular basement membrane development; glomerular filtration; heparan sulfate proteoglycan metabolic process; kidney development; negative regulation of fibroblast growth factor receptor signaling pathway; positive regulation of Wnt receptor signaling pathway |
NCBI Summary: | Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q8IWU5 |
NCBI GenInfo Identifier: | 33112446 |
NCBI Gene ID: | 55959 |
NCBI Accession: | Q8IWU5.1 |
UniProt Secondary Accession: | Q8IWU5,Q5JYE1, Q6UX86, Q96SG2, Q9H1H0, Q9UJR3, Q9ULH3 E1P5U6, |
UniProt Related Accession: | Q8IWU5 |
Molecular Weight: | 100,156 Da |
NCBI Full Name: | Extracellular sulfatase Sulf-2 |
NCBI Synonym Full Names: | sulfatase 2 |
NCBI Official Symbol: | SULF2 |
NCBI Official Synonym Symbols: | HSULF-2 |
NCBI Protein Information: | extracellular sulfatase Sulf-2 |
UniProt Protein Name: | Extracellular sulfatase Sulf-2 |
Protein Family: | Extracellular sulfatase |
UniProt Gene Name: | SULF2 |
UniProt Entry Name: | SULF2_HUMAN |
Antibodies | ELISA Kits |
Anti-SULF2 Antibody (CAB8803) | Human SULF2 / Sulfatase-2 ELISA Kit |
Human Extracellular sulfatase Sulf-2 (SULF2) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |