ST8SIA4 Antibody, HRP conjugated (PACO38083)
- SKU:
- PACO38083
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | ST8SIA4 Antibody, HRP conjugated (PACO38083) |
抗体コード: | PACO38083 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase protein (21-168AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Catalyzes the polycondensation of alpha-2,8-linked sialic acid, required for the synthesis of polysialic acid, (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells. |
シノニム: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (EC 2.4.99.-) (Alpha-2,8-sialyltransferase 8D) (Polysialyltransferase-1) (Sialyltransferase 8D) (SIAT8-D) (Sialyltransferase St8Sia IV) (ST8SiaIV), ST8SIA4, PST PST1 SIAT8D |
UniProt Protein Function: | ST8SIA4: Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells. Belongs to the glycosyltransferase 29 family. |
UniProt Protein Details: | Protein type:Transferase; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; EC 2.4.99.-; Membrane protein, integral Chromosomal Location of Human Ortholog: 5q21 Cellular Component: Golgi membrane; integral to Golgi membrane Molecular Function:alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; sialic acid binding Biological Process: axon guidance; nervous system development; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; protein modification process; protein amino acid glycosylation; protein amino acid N-linked glycosylation via asparagine; N-glycan processing; post-translational protein modification; oligosaccharide metabolic process; ganglioside biosynthetic process |
NCBI Summary: | The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q92187 |
NCBI GenInfo Identifier: | 2494834 |
NCBI Gene ID: | 7903 |
NCBI Accession: | Q92187.1 |
UniProt Secondary Accession: | Q92187,Q8N1F4, Q92693, A8KA07, G3V104, |
UniProt Related Accession: | Q92187 |
Molecular Weight: | 359 |
NCBI Full Name: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase |
NCBI Synonym Full Names: | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
NCBI Official Symbol: | ST8SIA4 |
NCBI Official Synonym Symbols: | PST; PST1; SIAT8D; ST8SIA-IV |
NCBI Protein Information: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase; SIAT8-D; ST8SiaIV; sialyltransferase 8D; polysialyltransferase-1; sialytransferase St8Sia IV; sialyltransferase St8Sia IV; alpha-2,8-sialyltransferase 8D; sialyltransferase 8 (alpha-2, 8-polysialytransferase) D; CMP-N-acetylneuraminate-poly-alpha-2,8-sialyl transferase |
UniProt Protein Name: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase |
UniProt Synonym Protein Names: | Alpha-2,8-sialyltransferase 8D; Polysialyltransferase-1; Sialyltransferase 8D; SIAT8-D; Sialyltransferase St8Sia IV; ST8SiaIV |
Protein Family: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase |
UniProt Gene Name: | ST8SIA4 |
UniProt Entry Name: | SIA8D_HUMAN |